About 19 results found for searched term "Dopamine Transporter" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2445 | Benztropine mesylate | Dopamine Receptor |
| Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate | ||
| Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Benztropine mesylate is a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects. Benztropine mesylate is also an anti-histamine agent and a dopamine re-uptake inhibitor. | ||
| M2886 | Nomifensine Maleate | Dopamine Receptor |
| (±)-Nomifensine maleat | ||
| Nomifensine is a dopamine reuptake inhibitor that increases the amount of synaptic dopamine available to receptors by blocking dopamine's re-uptake transporter. | ||
| M1559 | Clomipramine Hydrochloride | 5-HT Receptor |
| Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. | ||
| M6664 | Desipramine hydrochloride | Dopamine Receptor |
| Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively. | ||
| M7213 | Roxindole hydrochloride | Others |
| Roxindole hydrochloride is a dopamine D 2 autoreceptor agonist. Also has affinity for D 3, D 4, 5-HT 1A receptors and the 5-HT transporter. | ||
| M8175 | SF-22 | Others |
| Radioligand studies reveal that SF-22 also targets 5-HT2B and 5-HT6 serotonin receptors and dopamine transporter. | ||
| M8463 | FFN102 | Monoamine Transporter |
| FFN102 is a pH-responsive fluorescent false neurotransmitter that acts as a dopamine transporter substrate (DAT) and also a substrate for vesicular monoamine transporter 2 (VMAT2). | ||
| M13949 | Nomifensine | Dopamine Receptor |
| (±)-Nomifensin | ||
| Nomifensine is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. | ||
| M27764 | SKF-83566 hydrobromide | Dopamine Receptor |
| SKF-83566 hydrobromide is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF-83566 can be used for the research of parkinson’s disease and nicotine craving alleviation. | ||
| M27813 | CM398 | Sigma Receptor |
| CM398 is a highly selective, orally active sigma-2 receptor ligand (Ki=0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (Ki=32.90 nM) and serotonin transporters (Ki=244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice. | ||
| M30849 | 5,7-Dimethoxyluteolin | Dopamine Transporter |
| 5,7-Dimethoxyluteolin, a 5,7-dimethylluteolin derivative, is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM. | ||
| M30962 | (R)-Phenylpiracetam | Dopamine Transporter |
| MRZ 9547 | ||
| (R)-Phenylpiracetam (MRZ 9547) is a dopamine transporter (DAT) inhibitor (Ki: 14.8 μM; IC50: 65.5 μM). (R)-Phenylpiracetam can be used for the research of the neurological or neuropsychiatric disorders. | ||
| M30989 | SKF-83566 | Dopamine Receptor |
| SKF-83566 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF-83566 can be used for research of parkinson’s disease and nicotine craving alleviation. | ||
| M30990 | Adrenalone | Adrenergic Receptor |
| Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone is an inhibitor of dopamine β oxidase. Adrenalone is chemically similar to known norepinephrine transporter (NET) ligands with an IC50 of 36.9 μM. | ||
| M31235 | 13-Hydroxyisobakuchiol | Monoamine Transporter |
| Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol) is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). | ||
| M31244 | Bupropion morpholinol | Dopamine Transporter |
| Bupropion morpholinol (Hydroxy Bupropion) is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities. | ||
| M31245 | Dasotraline | Dopamine Transporter |
| Dasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. | ||
| M42670 | RTI 336 | Dopamine Transporter |
| RTI 336 is a phenyltropane analog, as well as a potent and selective dopamine transporter (DAT) inhibitor. | ||
| M42671 | Z1078601926 | Dopamine Transporter |
| Z1078601926 is an allosterical inhibitor of human dopamine transporter (hDAT). | ||
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