About 7 results found for searched term "Transthyretin (TTR)" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M40683 | Recombinant Human RBP4 (HEK293, C-His) | Cytokines and Growth Factors |
| Retinol-Binding Protein 4 | ||
| Human-retinol binding protein is a single-chain polypeptide with a molecular weight of approximately 21000 and one binding site for retinol and other forms of vitamin A. In plasma, RBP4-retinol forms a complex with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision. | ||
| M14778 | Tafamidis meglumine | Transthyretin (TTR) |
| Fx-1006A | ||
| Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. | ||
| M28920 | Dichlorophenyl-ABA | Transthyretin (TTR) |
| Dichlorophenyl-ABA is an inhibitor of transthyretin (TTR) amyloid fibril formation, inhibiting aggregate formation in more than 80% in TTR L55P-expressing cells. | ||
| M40947 | Inotersen | Transthyretin (TTR) |
| GSK-2998728; ISIS-420915 | ||
| Inotersen is an antisense oligonucleotide that inhibits the production of the hepatic transthyretin (TTR) protein. It can be used in studies related to TTR-mediated amyloidosis. | ||
| M40952 | Patisiran | Transthyretin (TTR) |
| Patisiran is a small double-stranded interfering RNA that targets sequences within the Transthyretin (TTR) messenger RNA and specifically inhibits hepatic synthesis of mutant and wild-type TTR. It can be used to study hereditary TTR amyloidosis. | ||
| M40955 | Vutrisiran | Transthyretin (TTR) |
| ALN-TTRsc02 | ||
| Vutrisiran is a liver-directed small interfering RNA (siRNA) that targets transthyretin protein (TTR) mRNA and can be used in TTR-mediated amyloidosis studies. | ||
| M42714 | AS-Patisiran | Transthyretin (TTR) |
| Patisiran is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. | ||
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