About 9 results found for searched term "Mitochondrial Related" (0.145 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2830 | Mdivi-1 | Dynamin |
| Mitochondrial division inhibitor 1 | ||
| Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. | ||
| M10756 | Flavokawain A | Apoptosis |
| CAS# 37951-13-6 | ||
| Flavokawain A is an anticarcinogenic agent, a chalcone found in kava extracts with antitumor activity. Flavokawain A induces apoptosis through Bax protein-dependent and mitochondrial-dependent apoptosis pathways. Flavokawain A has the potential to be used in bladder cancer related research. | ||
| M40536 | T0467 | Mitochondrial Related |
| T0467 is a potential PINK1-Parkin signaling activator that activates mitochondrial parkin translocation in a PINK1-dependent manner, but does not induce mitochondrial aggregation of PINK1 in dopaminergic neurons. It can be used in the study of Parkinson's disease and related disorders. | ||
| M40912 | Tricaprilin | Others |
| Trioctanoin; Glyceryl trioctanoate | ||
| Tricaprilin is an orally active medium chain triglyceride that improves mitochondrial metabolism by inducing a ketosis state. It can be used in studies related to Alzheimer's disease (AD). | ||
| M40980 | HU6 | Mitochondrial Related |
| HU6 is a mitochondrial oxidative phosphorylation uncoupler that can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M40989 | Azemiglitazone potassium | PPAR |
| MSDC-0602K | ||
| Azemiglitazone potassium is a thiazolidinediones that binds to PPARγ with an IC50 value of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). It can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M42885 | FGIN 1-43 | Others |
| FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids). | ||
| M45064 | MTK458 | Others |
| EP-0035985 | ||
| MTK458 is an orally active, brain-permeable PINK1 activator that binds to and stabilizes the active isoform of PINK1, thereby enhancing mitophagy and promoting mitochondrial autophagy (Mitophagy). It can be used in studies related to Parkinson's disease (PD). | ||
| M45348 | 4-Hydroperoxy cyclophosphamide | DNA Alkylator/Crosslinker |
| 4-Hydroperoxy cyclophosphamide, the active metabolite form of the precursor Cyclophosphamide, cross-links DNA and induces T-cell apoptosis independent of caspase receptor activation, as well as activating the mitochondrial death pathway through the generation of reactive oxygen species (ROS). It can be used in studies related to rheumatoid arthritis and autoimmune diseases. | ||
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