About 24 results found for searched term "Ephrin Receptor" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2388 | Amitriptyline hydrochloride | 5-HT Receptor |
| Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively. | ||
| M3043 | Synephrine hydrochloride | Adrenergic Receptor |
| Oxedrine hydrochloride | ||
| SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist. | ||
| M3330 | Phenylephrine hydrochloride | Adrenergic Receptor |
| Phenylephrine hydrochloride is a selective α1-adrenergic receptor agonist. | ||
| M5424 | Asenapine maleate | 5-HT Receptor |
| Org 5222 | ||
| Asenapine maleate is a high-affinity antagonist of various receptors including serotonin receptors (5-HT), norepinephrine (NA), dopamine receptors, and histamine receptors, and can be used in studies related to neurodivergent disorders as well as depressive manic depression. | ||
| M8327 | D,L-Metanephrine hydrochloride | TAAR |
| Metanephrine is an endogenous metabolite of epinephrine, formed by catechol-O-methyltransferase activity, as well as a biomarker of cancer and can be used to diagnose pheochromocytoma. In addition, Metanephrine is a potent agonist of the trace amine-associated receptor TAAR1. | ||
| M9264 | Norepinephrine | Adrenergic Receptor |
| Levarterenol; Levophed; Arterenol | ||
| Norepinephrine is generally considered to be a β1-selective adrenergic receptor agonist with EC50 of 5.37 μM. | ||
| M10684 | Phenylephrine | Adrenergic Receptor |
| (R)-(-)-Phenylephrine; L-Phenylephrine | ||
| Phenylephrine is a selective α1- adrenergic receptor agonists. | ||
| M10848 | LP-922761 | Others |
| LP-922761 is a potent, selective, orally active AAK1 inhibitor in enzymatic and cell analysis IC50 4.8 nM and 7.6 nM, respectively. LP-922761 also inhibits BMP-2-induced protein kinase (BIKE),IC50 24 nM. LP-922761 has no significant activity against cell GAK, opioids, epinephrine alpha2, or GABAa receptors. | ||
| M13896 | Norepinephrine hydrochloride | Adrenergic Receptor |
| Levarterenol hydrochloride; L-Noradrenaline hydrochloride | ||
| Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors. | ||
| M13949 | Nomifensine | Dopamine Receptor |
| (±)-Nomifensin | ||
| Nomifensine is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. | ||
| M20404 | Tryptamine | TAAR |
| Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA). Tryptamine is a selective, blood-brain-penetrating 5-HT4 receptor agonist (EC50=1-3 mM) and an endogenous ligand of the aryl hydrocarbon receptor (AHR) (Kd=10-50 nM). Tryptamine promotes intestinal anion secretion and fluid transport by activating G protein-coupled receptors (GPCRs). | ||
| M20793 | Amitriptyline | Serotonin Transporter |
| MK-230; N-750; Ro41575 | ||
| Amitriptyline (MK-230, N-750, Ro41575) is an inhibitor of the serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki values of 3.45 nM and 13.3 nM, respectively, and also inhibits the histamine receptor H1, the histamine receptor H4, 5-HT2, and the Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. It can also inhibit histamine receptor H1, histamine receptor H4, 5-HT2 and Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively, and can be used in studies of depression and neuropathic pain. | ||
| M21796 | Asenapine hydrochloride | 5-HT Receptor |
| Asenapine hydrochloride is a high-affinity antagonist of various receptors including serotonin receptors (5-HT), norepinephrine (NA), dopamine receptors, and histamine receptors, and is used in studies related to neurodivergent disorders, as well as depressive manic depression. | ||
| M30309 | Setiptiline | 5-HT Receptor |
| Org-8282 | ||
| Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine. | ||
| M30707 | Setiptiline maleate | 5-HT Receptor |
| MO-8282 | ||
| Setiptiline maleate (MO-8282 maleate) is a serotonin receptor antagonist. Setiptiline maleate is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline maleate acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine. | ||
| M30979 | Dextromilnacipran | Serotonin Transporter |
| (1R,2S)-milnacipran; F2696; Levomilnacipran | ||
| Dextromilnacipran (F2696; (1R,2S)-milnacipran), an enantiomer of milnacipran, is a selective serotonin and norepinephrine (5-HT/NE) reuptake inhibitor. Dextromilnacipran also is a human alpha-adrenergic receptor antagonist, with an IC50 of 3.4 μM. | ||
| M31209 | Hydroxybupropion | Adrenergic Receptor |
| Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion inhibits norepinephrine uptake with an IC50 value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonist. | ||
| M31218 | Neuropeptide Y (3-36) (human, rat) | Neuropeptide Receptor |
| Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. Neuropeptide Y (3-36) (human, rat) is a NPY metabolite formed from dipeptidyl peptidase-4 (DPP4). Neuropeptide Y (3-36) (human, rat) decreases release of norepinephrine via the Y2 receptor. | ||
| M31234 | Metapramine | GluR |
| Metapramine (19560 RP) is an antidepressant agent, inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel. | ||
| M31244 | Bupropion morpholinol | Dopamine Transporter |
| Bupropion morpholinol (Hydroxy Bupropion) is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities. | ||
| M40635 | DL-Norepinephrine hydrochloride | Adrenergic Receptor |
| DL-Norepinephrine hydrochloride is a synthetic phenylephrine that mimics the sympathomimetic effects of endogenous norepinephrine and is also a neurotransmitter targeting the adrenergic receptors α1 and β1, which have been shown to lower the subendocardial partial pressure of oxygen. | ||
| M56121 | Amidephrine hydrochloride | Adrenergic Receptor |
| Amidephrine (hydrochloride) is an adrenergic receptor (AR) agonist. | ||
| M56091 | Tedatioxetine | 5-HT Receptor |
| Tedatioxetine (Lu AA24530) acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. | ||
| M56076 | Tedatioxetine hydrobromide | 5-HT Receptor |
| Tedatioxetine (Lu AA24530) hydrobromide acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. | ||
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