About 7 results found for searched term "Cuproptosis" (0.124 seconds)
Cat.No. | Name | Target |
---|---|---|
M2083 | Elesclomol | Cuproptosis |
STA-4783 | ||
Elesclomol (STA-4783) is a novel oxidative stress inducer that acts on tumor cells and promotes their apoptosis, and is a strong copper ion-carrier that can be used for cuproptosis studies. | ||
M2891 | NSC 319726 | Cuproptosis |
NSC-319726; ZMC1 | ||
NSC 319726 is a p53(R175) mutant activator that inhibits the growth of p53(R175) mutant cells and acts on p53(R175) mutant cells with IC50 of 8 nM, which has no inhibition on p53 wild-type cells. NSC 319726 is a potent copper ion-carrier that can be used in cuproptosis studies. | ||
M3137 | Zinc Pyrithione | Cuproptosis |
ZnPyr | ||
Zinc Pyrithione is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies. | ||
M3390 | Disulfiram | Pyroptosis |
Tetraethylthiuram disulfide; TETD | ||
Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1). Disulfiram is used in the study of chronic alcoholism, with acute sensitivity to alcohol, and is a potent copper ion-carrier that can be used in cuproptosis studies. | ||
M7455 | UK-5099 | Monocarboxylate Transporter (MCT) |
PF-1005023 | ||
UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC), it inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM. UK-5099 is also a cuproptosis inhibitor. | ||
M55219 | UM4118 | Cuproptosis |
UM-4118 | ||
UM4118 is a copper ionophore which can initiate a mitochondrial-based noncanonical form of cell death known as cuproptosis. UM4118 exhibits high sensitivity in SF3B1-mutated and adverse risk acute myeloid leukemia (AML), and can be used for AML research. | ||
M58415 | Cu(II)-Elesclomol | Cuproptosis |
Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol. Cu(II)-Elesclomol induces cuproptosis. Cu(II)-Elesclomol also inducesapoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells. |
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