About 30 results found for searched term "Antifungal" (0.062 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1958 | Natamycin | Antibiotic |
| Natacyn; Pimaricin | ||
| Natamycin is an antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. | ||
| M2247 | Carmofur | DNA/RNA Synthesis |
| HCFU | ||
| Carmofur is a pyrimidine analog that is a prodrug of 5-fluorouracil (5-FU), which inhibits DNA Synthesis and has better antiproliferative activity than 5-FU. Carmofur is an inhibitor of Acidic Ceramidase (ASAH1) and a potential lead compound for non-cancer diseases such as Krabbe disease, acute lung injury (ALI), Parkinson's disease (PD), dementia, etc. Carmofur also has antifungal and antimicrobial properties. | ||
| M2267 | Resveratrol | Sirtuin |
| trans-Resveratrol; SRT501 | ||
| Resveratrol is a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. | ||
| M2481 | Butenafine hydrochloride | Antibiotic |
| KP-363 | ||
| Butenafine hydrochloride is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. | ||
| M2524 | Climbazole | Antibiotic |
| BAY-e 6975 | ||
| Climbazole is a broad-spectrum imidazole antifungal agent that can provide anti-dandruff benefits. | ||
| M2874 | Naftifine hydrochloride | Antibiotic |
| Naftifine is an allylamine antifungal compound for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme. | ||
| M2994 | Salicylanilide | HIV Protease |
| 2-Hydroxybenzanilide | ||
| Salicylanilides are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities. | ||
| M3005 | Sertaconazole nitrate | Antibiotic |
| FI-7045 | ||
| Sertaconazole nitrate is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections. | ||
| M3036 | Sulconazole Nitrate | Antibiotic |
| Sulconazole Nitrate is an imidazole derivative with broad-spectrum antifungal activity. | ||
| M3182 | Luliconazole | Antibiotic |
| NND 502 | ||
| Luliconazole is a novel topical antifungal imidazole with broad-spectrum and potent antifungal activity. | ||
| M3290 | Nystatin | Antibiotic |
| Fungicidin; Mycostatin | ||
| Nystatin (Fungicidin) is a polyene antifungal antibiotic to which many molds, mycoplasma and yeasts are sensitive, including Candida spp. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. | ||
| M3407 | Terbinafine hydrochloride | Others |
| Terbinafine hydrochloride is a hydrochloride salt of terbinafine that is a synthetic allylamine antifungal and a squalene epoxidase inhibitor with an IC50 of 30 nM for Candida albicans. | ||
| M3489 | Econazole nitrate | Antibiotic |
| Econazole nitrate (Spectazole) is an imidazole class antifungal medication. | ||
| M3541 | Miconazole Nitrate | Antibiotic |
| R18134 nitrate | ||
| Miconazole Nitrate is an imidazole antifungal agent that is used topically and by intravenous infusion. | ||
| M3593 | Ciclopirox ethanolamine | Anti-infection |
| Ciclopirox olamine | ||
| Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. | ||
| M3669 | Micafungin Sodium | Antibiotic |
| FK463 sodium | ||
| Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, it is an antifungal agent. | ||
| M3733 | Pneumocandin B0 | Antibiotic |
| L-688786 | ||
| Pneumocandin B0 (L-688786) is a key intermediate in the synthesis of the antifungal agent, Cancidas, has led to the identification of several materials with potential for improved performance. | ||
| M3953 | Voriconazole | Cytochrome P450 (e.g. CYP17) |
| UK-109496 | ||
| Voriconazole (UK-109496) is an inhibitor of 14α-lanosterol demethylase with IC50 value of 53 nM. Voriconazole (UK-109496) is also a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. | ||
| M4004 | Hyperoside | Apoptosis |
| Hyperoside is a potent natural activator of Nur77 receptor, which can be potentially used for the research of occlusive vascular diseases. Hyperoside is also a NF-κB inhibitor. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis. | ||
| M1587 | Hydroxy Itraconazole | Antibiotic |
| Hydroxy Itraconazole; R-63373 | ||
| Itraconazole metabolite Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. | ||
| M4007 | Isoliquiritin | Antibiotic |
| Isoliquiritin is isolated from licorice root and inhibits angiogenesis and duct formation. Isoliquiritin also has antidepressant and antifungal activity. | ||
| M4294 | Magnoflorine-iodide | Antibiotic |
| Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide | ||
| (+) -magnoflorine iodide (Magnoflorine iodide) is an apomorphine alkaloid from Acoruscalamus that reduces the formation of c. albicans biofilms. (+) -magnoflorine iodide has antifungal activity, antioxidant and antidiabetic effects. | ||
| M4302 | Solasodine | p53 |
| Purapuridine; Solancarpidine; Solasodin | ||
| Solasodine (Purapuridine) is a steroid alkaloid found in solanaceae plants. Solasodine has neuroprotective, antifungal, antihypertensive, anticancer, antiatherosclerotic, antiandrogen and anti-inflammatory activities. | ||
| M4469 | Cinnamaldehyde | PPAR |
| Cinnamaldehyde is a naturally occurring flavonoid found in the bark of Cinnamomum cinnamomi and other Cinnamomum species such as camphor and cinnamon, and can act through a variety of signaling pathways, including PPARs, AMPK, PI3K/IRS-1, RBP4-GLUT4, ERK/JNK/p38MAPK, TRPA1-ghrelin, and the Nrf2 pathways.Cinnamaldehyde also has the potential to modulate the activities of PTP1B and α-amylase with antifungal activity and antioxidant activity. | ||
| M4472 | Cornin | Anti-infection |
| Verbenalin is a verbenoside, which has anti-inflammatory, antifungal and antiviral activities. Verbenalin is used to study prostatitis. Verbenalin reduces cerebral ischemia-reperfusion injury. | ||
| M4487 | Peucedanol | Antibiotic |
| Peucedanol methyl ether | ||
| Ulopterol, a coumarin isolated from the leaves of Toddalia Asiatica (L.) Lam, has strong antibacterial and antifungal activities. | ||
| M4517 | Proanthocyanidins | Akt |
| Proanthocyanidins can be used as antioxidant and anti-cancers agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties. | ||
| M4557 | Dictamine | Apoptosis |
| Dictamnine; Dectamine | ||
| Dictamnine (Dictamine) is cytotoxic to human cervical and colon cancer cells, and also has antibacterial and antifungal activities. | ||
| M4632 | Xanthatin | Wnt/beta-catenin |
| Xanthatin has antibacterial and antifungal activies against MRSA. | ||
| M4638 | Pseudolaric-acid | Antibiotic |
| NSC615487 | ||
| Pseudolaric C is a diterpenoid acid isolated from the root bark of Pseudolarix Kaempferi Gorden with antifungal activity. | ||
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