About 31 results found for searched term "Reverse Transcriptase" (0.06 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41242 | M-MLV Reverse transcriptase | Reverse Transcriptase |
| M-MLV Reverse transcriptase (M-MLV RT) is a kind of Reverse transcriptase, from the moroni mouse leukemia virus (MoMLV). | ||
| M2137 | Stavudine | Reverse Transcriptase |
| d4T | ||
| Stavudine (D4T) is a potent inhibitor of HIV-1 reverse transcriptase in vitro. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis. | ||
| M2173 | Delavirdine mesylate | HIV Protease |
| U-90152 | ||
| Delavirdine mesylate is a nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). | ||
| M2575 | Dapivirine | Reverse Transcriptase |
| TMC120; R147681 | ||
| Dapivirine is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations. | ||
| M2694 | Etravirine | Reverse Transcriptase |
| R-165335 | ||
| Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. | ||
| M2713 | Foscarnet Sodium | Others |
| Phosphonoformate | ||
| Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs. | ||
| M2980 | Rilpivirine (R278474) | Reverse Transcriptase |
| R278474, TMC278 | ||
| Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). | ||
| M3205 | Zidovudine | Reverse Transcriptase |
| Azidothymidine; AZT; ZDV | ||
| Zidovudine is a reverse transcriptase inhibitor. | ||
| M3342 | Emtricitabine | Reverse Transcriptase |
| BW1592 | ||
| Emtricitabine is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM. | ||
| M3347 | Zalcitabine | Reverse Transcriptase |
| ddC; Dideoxycytidine; 2',3'-Dideoxycytidine | ||
| Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). | ||
| M3352 | Lamivudine (BCH-189) | Reverse Transcriptase |
| BCH-189 | ||
| Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI) with an IC50 of 2.7 mM. Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS. | ||
| M3355 | Didanosine | Reverse Transcriptase |
| 2',3'-Dideoxyinosine; ddI | ||
| Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM. | ||
| M3381 | Nevirapine | Reverse Transcriptase |
| BI-RG 587; NSC 641530; NVP | ||
| Nevirapine (NSC 641530) is a potent, specific non-nucleoside reverse transcriptase inhibitor (NNRTIs) that non-competitively inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with a Ki of 220 nM. Nevirapine (NSC 641530) can be used in AIDS-related researchs. | ||
| M3654 | Nelfinavir Mesylate | HIV Protease |
| AG-1343 | ||
| Nelfinavir is a potent HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. | ||
| M5049 | Abacavir | HIV Protease |
| Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV. | ||
| M5050 | Adefovir Dipivoxil | Reverse Transcriptase |
| GS 0840 | ||
| Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. | ||
| M5051 | Tenofovir | Reverse Transcriptase |
| GS 1278; PMPA; TDF | ||
| Tenofovir is a nucleotide reverse transcriptase inhibitor used in studies related to HIV and chronic hepatitis B (HBV). | ||
| M5052 | Tenofovir Disoproxil Fumarate | HIV Protease |
| Tenofovir DF | ||
| Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral compounds, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. | ||
| M5605 | Efavirenz | Reverse Transcriptase |
| Sustiva, Stocrin, DMP-266 | ||
| Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture. | ||
| M6274 | Tenofovir Disoproxil | HIV Protease |
| Bis(POC)-PMPA; GS 4331 | ||
| Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. | ||
| M7963 | Nalidixic acid sodium salt | Antibiotic |
| Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Nalidixic acid sodium salt is a quinolone antibiotic, it is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. | ||
| M8265 | Adefovir | Others |
| Adefovir is an antiviral compound that inhibits hepatitis B virus (HBV) DNA polymerase (reverse transcriptase) after intracellular conversion to adefovir diphosphate. | ||
| M10364 | Tenofovir hydrate | HIV Protease |
| GS 1278 hydrate; PMPA hydrate | ||
| Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. | ||
| M18702 | Isobavachromene | p38 MAPK |
| 4-Hydroxylonchocarpin | ||
| Isobavachromene (4-Hydroxylonchocarpin) increases phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin has diverse pharmacological activities, including antibacterial, antifungal, anticancer, antireverse transcriptase, antitubercular, antimalarial, anti-inflammatory and antioxidant activities. | ||
| M19373 | Corydine | Reverse Transcriptase |
| Corydine is efficient on inhibiting reverse transcriptase (RT) activity with an IC50 of 356.8 μg/mL. Corydine displays significant in vitro anti-HIV potential, inhibiting 40% of the HIV-1 reverse transcriptase enzyme activity at a concentration of 450 μg/䲧瓰Ỵ瓱 㧀瓯羹瓗 | ||
| M20054 | WAY-278459-A | Others |
| WAY-278459-A is a inhibitor of wild type and mutant HIV-1 reverse transcriptase | ||
| M20364 | WAY-300700 | HIV Protease |
| WAY-300700 is a HIV-1 non-nucleoside reverse transcriptase inhibitor. | ||
| M20483 | 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride | Reverse Transcriptase |
| 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is a HIV-1 RT (HIV reverse transcriptase) inhibitor. | ||
| M20577 | Doravirine | Reverse Transcriptase |
| MK1439 | ||
| Doravirine (MK-1439) is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. | ||
| M20702 | Alovudine | Reverse Transcriptase |
| CL 184824, FddThd, FLT, MIV-310 | ||
| 3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer. | ||
| M20710 | ABX464 | Anti-infection |
| SPL-464; Obefazimod | ||
| ABX464 is a reverse transcriptase (RT) inhibitor with anti-HIV activity that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from five different donors, with IC50 values between 0.1 μM and 0.5 μM, and can be used in studies related to ulcerative colitis. | ||
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