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 About 31 results found for searched term "Reverse Transcriptase" (0.087 seconds)

Cat.No.  Name Target
M41242 M-MLV Reverse transcriptase Reverse Transcriptase
M-MLV Reverse transcriptase (M-MLV RT) is a kind of Reverse transcriptase, from the moroni mouse leukemia virus (MoMLV).
M2137 Stavudine Reverse Transcriptase
Stavudine (D4T) is a potent inhibitor of HIV-1 reverse transcriptase in vitro. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis.
M2173 Delavirdine mesylate HIV Protease
Delavirdine mesylate is a nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1).
M2575 Dapivirine Reverse Transcriptase
TMC120; R147681
Dapivirine is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM.
M2694 Etravirine Reverse Transcriptase
Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
M2713 Foscarnet Sodium Others
Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.
M2980 Rilpivirine (R278474) Reverse Transcriptase
R278474, TMC278
Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM).
M3205 Zidovudine Reverse Transcriptase
Azidothymidine; AZT; ZDV
Zidovudine is a reverse transcriptase inhibitor.
M3342 Emtricitabine Reverse Transcriptase
Emtricitabine is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM.
M3347 Zalcitabine Reverse Transcriptase
ddC; Dideoxycytidine; 2',3'-Dideoxycytidine
Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).
M3352 Lamivudine (BCH-189) Reverse Transcriptase
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI) with an IC50 of 2.7 mM. Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS.
M3355 Didanosine Reverse Transcriptase
2',3'-Dideoxyinosine; ddI
Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.
M3381 Nevirapine Reverse Transcriptase
BI-RG 587; NSC 641530; NVP
Nevirapine (NSC 641530) is a potent, specific non-nucleoside reverse transcriptase inhibitor (NNRTIs) that non-competitively inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with a Ki of 220 nM. Nevirapine (NSC 641530) can be used in AIDS-related researchs.
M3654 Nelfinavir Mesylate HIV Protease
Nelfinavir is a potent HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.
M5049 Abacavir HIV Protease
Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV.
M5050 Adefovir Dipivoxil Reverse Transcriptase
GS 0840
Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir.
M5051 Tenofovir Reverse Transcriptase
GS 1278; PMPA; TDF
Tenofovir is a nucleotide reverse transcriptase inhibitor used in studies related to HIV and chronic hepatitis B (HBV).
M5052 Tenofovir Disoproxil Fumarate HIV Protease
Tenofovir DF
Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral compounds, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.
M5605 Efavirenz Reverse Transcriptase
Sustiva, Stocrin, DMP-266
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
M6274 Tenofovir Disoproxil HIV Protease
Bis(POC)-PMPA; GS 4331
Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
M7963 Nalidixic acid sodium salt Antibiotic
Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Nalidixic acid sodium salt is a quinolone antibiotic, it is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations.
M8265 Adefovir Others
Adefovir is an antiviral compound that inhibits hepatitis B virus (HBV) DNA polymerase (reverse transcriptase) after intracellular conversion to adefovir diphosphate.
M10364 Tenofovir hydrate HIV Protease
GS 1278 hydrate; PMPA hydrate
Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
M19373 Corydine Reverse Transcriptase
Corydine is efficient on inhibiting reverse transcriptase (RT) activity with an IC50 of 356.8 μg/mL. Corydine displays significant in vitro anti-HIV potential, inhibiting 40% of the HIV-1 reverse transcriptase enzyme activity at a concentration of 450 μg/䲧瓰Ỵ瓱㧀瓯羹瓗
M20054 WAY-278459-A Others
WAY-278459-A is a inhibitor of wild type and mutant HIV-1 reverse transcriptase
M20364 WAY-300700 HIV Protease
WAY-300700 is a HIV-1 non-nucleoside reverse transcriptase inhibitor.
M20483 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride Reverse Transcriptase
4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is a HIV-1 RT (HIV reverse transcriptase) inhibitor.
M20577 Doravirine Reverse Transcriptase
Doravirine (MK-1439) is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay.
M20702 Alovudine Reverse Transcriptase
CL 184824, FddThd, FLT, MIV-310
3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
M20710 ABX464 Anti-infection
SPL-464; Obefazimod
ABX464 is a reverse transcriptase (RT) inhibitor with anti-HIV activity that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from five different donors, with IC50 values between 0.1 μM and 0.5 μM, and can be used in studies related to ulcerative colitis.
M20783 Tenofovir alafenamide hemifumarate Reverse Transcriptase
TAF hemifumarate, GS-7340 hemifumarate
Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.

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