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About 30 results found for searched term "Reverse Transcriptase" (0.033 seconds)
| Cat.No. | Name | Information |
|---|---|---|
| M2137 | Stavudine | Stavudine (D4T) is a potent inhibitor of HIV-1 reverse transcriptase in vitro. |
| M2173 | Delavirdine mesylate | Delavirdine mesylate is a nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). |
| M2575 | Dapivirine | Dapivirine is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. |
| M2694 | Etravirine | Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. |
| M2713 | Foscarnet Sodium | Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs. |
| M2980 | Rilpivirine (R278474) | Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). |
| M3205 | Zidovudine | Zidovudine is a reverse transcriptase inhibitor. |
| M3342 | Emtricitabine | Emtricitabine is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM. |
| M3347 | Zalcitabine | Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). |
| M3352 | Lamivudine (BCH-189) | Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI) with an IC50 of 2.7 mM. Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS. |
| M3355 | Didanosine | Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM. |
| M3381 | Nevirapine | Nevirapine (NSC 641530) is a potent, specific non-nucleoside reverse transcriptase inhibitor (NNRTIs) that non-competitively inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with a Ki of 220 nM. Nevirapine (NSC 641530) can be used in AIDS-related researchs. |
| M3654 | Nelfinavir Mesylate | Nelfinavir is a potent HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
| M5049 | Abacavir | Abacavir is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. |
| M5050 | Adefovir Dipivoxil | Adefovir Dipivoxil is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV). |
| M5051 | Tenofovir | Tenofovir blocks reverse transcriptase and hepatitis B virus infections. |
| M5052 | Tenofovir Disoproxil Fumarate | Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral compounds, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. |
| M5605 | Efavirenz | Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture. |
| M6274 | Tenofovir Disoproxil | Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. |
| M7963 | Nalidixic acid sodium salt | Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. |
| M8265 | Adefovir | Adefovir is an antiviral compound that inhibits hepatitis B virus (HBV) DNA polymerase (reverse transcriptase) after intracellular conversion to adefovir diphosphate. |
| M10364 | Tenofovir hydrate | Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. |
| M20054 | WAY-278459-A | WAY-278459-A is a inhibitor of wild type and mutant HIV-1 reverse transcriptase |
| M20364 | WAY-300700 | WAY-300700 is a HIV-1 non-nucleoside reverse transcriptase inhibitor. |
| M20483 | 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride | 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is a HIV-1 RT (HIV reverse transcriptase) inhibitor. |
| M20577 | Doravirine (MK-1439) | Doravirine (MK-1439) is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. |
| M20702 | Alovudine | 3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer. |
| M20783 | Tenofovir alafenamide hemifumarate | Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. |
| M20784 | Tenofovir alafenamide fumarate | Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. |
| M21356 | Ulonivirine | Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity.Ulonivirine is used in the study of HIV-1 infection. |
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