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Adefovir is an antiviral compound that inhibits hepatitis B virus (HBV) DNA polymerase (reverse transcriptase) after intracellular conversion to adefovir diphosphate.
| Molecular Weight | 273.19 |
| Formula | C8H12N5O4P |
| CAS Number | 106941-25-7 |
| Solubility (25°C) | 0.1 M NaOH: ≥5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Morris Sherman. Why adefovir is not yet available in Canada
[3] David Mutimer. Adefovir-lamivudine combination therapy and hepatitis B viral kinetics
[5] Yi-min Mao, et al. Adefovir dipivoxil-A new drug for hepatitis B
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