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Anti-infection Anti-infection

Inhibitors

Cat.No.  Name Information
M1959 Oseltamivir Oseltamivir is a potent and selective inhibitor of influenza virus neuraminidase enzyme.
M5055 Peramivir Peramivir is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
M1707 Entecavir Monohydrate Entecavir Hydrate is a class of antiviral compounds.
M3357 Telbivudine Telbivudine is an antiviral compound used in hepatitis B research.
M3669 Micafungin Sodium Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis.
M10594 PF-07321332 (Nirmatrelvir) PF-07321332 (Nirmatrelvir) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme.
M10574 Indolicidin Indolicidin is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils.
M10543 Tenuazonic acid Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate.
M10502 ELQ-300 Elq-300 is an antimalarial drug available for biological research and is also an effective oral cytochrome BC1 complex (CYT BC1) reduction (Qi) site inhibitor.
M10473 MK-3118 MK-3118 is a novel glucan synthase inhibitor with activity against many echinocandin-resistant strains of Candida due to differential avidity for the target site compared to echinocandins.
M10444 Oteseconazole Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd <39 nM).
M10421 Sodium citrate (dihydrate) Sodium citrate dehydrate is an anticoagulant and also used as a buffer and food preservatives.
M10360 Arteannuin B Arteannuin B co-occurs with artemisinin, Arteannuin B shows anti-SARS-CoV-2 potential with an EC50 of 10.28 μM.
M10359 Dihydroartemisinic acid Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
M10339 Fexinidazole Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent.
M10241 Polymyxin B nonapeptide TFA Polymyxin B nonapeptide TFA is a cyclic peptide from the naturally occurring peptide polymyxin B, it can increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics.
M10232 Cefotaxime Cefotaxime is an inhibitor of penicillin binding protein.
M10178 Cefoperazone sodium Cefoperazone sodium is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
M10163 Baloxavir marboxil Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
M10148 Juglone Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity.
M10127 Azathramycin Azathramycin is an antibiotic, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.
M10084 AMY-101 acetate AMY-101 acetate is a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM).
M10082 Amodiaquine Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.
M10031 Lysozyme (from egg white) Lysozyme (from egg white) is a bactericidal enzyme present in chicken eggs, and it lyses gram-positive bacteria.
M10028 Phe-Arg-β-naphthylamide 2HCl Phe-Arg-β-naphthylamide 2HCl is an efflux pump inhibitor (EPI), it acts on the major multidrug resistance efflux transporters of Gram-negative bacteria.



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