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Anti-infection Anti-infection

Cat.No.  Name Information
M1959 Oseltamivir Oseltamivir is a potent and selective inhibitor of influenza virus neuraminidase enzyme.
M5055 Peramivir Peramivir is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
M5083 β-Cyclodextrin β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
M1707 Entecavir Monohydrate Entecavir Hydrate is a class of antiviral compounds.
M3357 Telbivudine Telbivudine is an antiviral compound used in hepatitis B research.
M1695 Cidofovir Cidofovir (Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis.
M4718 Dendrobine Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine has antiviral activity against influenza A virus, IC50 values for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2) were 3.39 μM, 2.16 μM and 5.32 μM, respectively.
M10421 Sodium citrate (dihydrate) Sodium citrate dehydrate is an anticoagulant and also used as a buffer and food preservatives.
M3222 Peramivir Trihydrate Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
M4789 Isoscopoletin Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in artemisia argyi leaves. Isoscopoletin showed significant inhibition of cell proliferation, with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and CEM/ADR5000 drug-resistant subline, respectively. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication.
M13448 Letermovir (AIC246) Letermovir (AIC246) is a novel and potent anti-CMV compound that targets viral terminal enzyme complexes and is active in viruses that are resistant to DNA polymerase inhibitors.
M13372 Brincidofovir Brincidofovir (CMX001), a lipid-coupled precursor compound of Cidofovir, has long-lasting antiviral effects and is active against a wide range of DNA viruses. These include cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomavirus, papillomavirus, poxvirus, and mixed double-stranded DNA virus infections.
M11318 Silymarin Silymarin is an extract of Silybum marianum. Silymarin is a potent sarS-COV-2 major protease (Mpro) inhibitor. Silymarin significantly reduced tumor cell proliferation, angiogenesis, and insulin resistance. Silymarin has chemoprophylaxis against hepatocellular carcinoma (HCC). Silymarin has the potential to be used in COVID-19 research.
M11199 Myriocin Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent serine-palmitoyl-transferase Inhibitors are the key to the synthesis of sphingolipids from scratch.
M10763 Maribavir Maribavir is an effective inhibition of wild-type pUL97-catalyzed histone phosphorylation,IC50 3 nM. Maribavir acts effectively against HCMV and Epstein-Barr virus (EBV).
M10754 Avermectin B1 Avermectin B1 (Abamectin) is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy.
M10700 RG7834 RG7834 (RO 7020322) is a highly selective, oral HBV inhibitor that effectively inhibits HBV antigens HBsAg, HBeAg, and HBV DNA in dHepaRG cells.IC50 The values are 2.8, 2.6, and 3.2 nM, respectively.
M10681 Bemnifosbuvir hemisulfate Bemnifosbuvir hemisulfate (AT-527) is a guanosine nucleotide prodrug and a potent orally active inhibitor of HCV viral replication. Bemnifosbuvir hemisulfate effectively inhibits SARS-CoV-2 (COVID-19) infection (EC90=0.47 μM). Bemnifosbuvir hemisulfate has whole-genotype antiviral activity.
M10646 GRP-60367 hydrochloride GRP-60367 hydrochloride is a first-in-class potent and selective inhibitor of rabies virus (RABV) entry that specifically targets the RABV G protein.
M10594 PF-07321332 (Nirmatrelvir) PF-07321332 (Nirmatrelvir) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme.
M10574 Indolicidin Indolicidin is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils.
M10543 Tenuazonic acid Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate.
M10502 ELQ-300 Elq-300 is an antimalarial drug available for biological research and is also an effective oral cytochrome BC1 complex (CYT BC1) reduction (Qi) site inhibitor.
M10444 Oteseconazole Oteseconazole (VT-1161) is an antifungal compound with oral activity that is highly selective for CYP51. It can effectively bind to and inhibit CYP51 of N. albicans (Kd <39 nM), but shows no obvious effect on human CYP51
M10360 Arteannuin B Arteannuin B co-occurs with artemisinin, Arteannuin B shows anti-SARS-CoV-2 potential with an EC50 of 10.28 μM.
M10359 Dihydroartemisinic acid Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
M10339 Fexinidazole Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent.
M10232 Cefotaxime Cefotaxime is an inhibitor of penicillin binding protein.
M10163 Baloxavir marboxil Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
M10148 Juglone Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity.

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