| Cat.No. | Name | Information |
|---|---|---|
| M1959 | Oseltamivir | Oseltamivir is a potent and selective inhibitor of influenza virus neuraminidase enzyme. |
| M5055 | Peramivir | Peramivir is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM. |
| M1707 | Entecavir Monohydrate | Entecavir Hydrate is a class of antiviral compounds. |
| M3357 | Telbivudine | Telbivudine (Epavudine) is an orally active, potent antiviral inhibitor of hepatitis B virus (HBV) replication. Telbivudine is an antiviral compound used in hepatitis B research. |
| M1695 | Cidofovir | Cidofovir (Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis. |
| M4718 | Dendrobine | Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine has antiviral activity against influenza A virus, IC50 values for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2) were 3.39 μM, 2.16 μM and 5.32 μM, respectively. |
| M3222 | Peramivir Trihydrate | Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM. |
| M4789 | Isoscopoletin | Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in artemisia argyi leaves. Isoscopoletin showed significant inhibition of cell proliferation, with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and CEM/ADR5000 drug-resistant subline, respectively. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication. |
| M10082 | Amodiaquine | Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent. |
| M7775 | 3-Deazaadenosine | 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM, possesses antiviral activity inhibitor of leukocyte adhesion to TNF-treated endothelial cells. |
| M13448 | Letermovir (AIC246) | Letermovir (AIC246) is a novel and potent anti-CMV compound that targets viral terminal enzyme complexes and is active in viruses that are resistant to DNA polymerase inhibitors. |
| M13372 | Brincidofovir | Brincidofovir (CMX001), a lipid-coupled precursor compound of Cidofovir, has long-lasting antiviral effects and is active against a wide range of DNA viruses. These include cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomavirus, papillomavirus, poxvirus, and mixed double-stranded DNA virus infections. |
| M11318 | Silymarin | Silymarin is an extract of Silybum marianum. Silymarin is a potent sarS-COV-2 major protease (Mpro) inhibitor. Silymarin significantly reduced tumor cell proliferation, angiogenesis, and insulin resistance. Silymarin has chemoprophylaxis against hepatocellular carcinoma (HCC). Silymarin has the potential to be used in COVID-19 research. |
| M11199 | Myriocin | Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent serine-palmitoyl-transferase Inhibitors are the key to the synthesis of sphingolipids from scratch. |
| M10884 | YH-53 | YH-53 IS AN EFFECTIVE ONE 3CLpro Inhibitor, 3CL against SARS-CoV-1pro and SARS-CoV-2 3CLpro target Ki The values are 6.3 nM and 34.7 nM, respectively. YH-53 strongly blocks SARS-CoV-2 replication. YH-53 is a peptide-mimetic compound with unique benzothiazolidinone. |
| M10763 | Maribavir | Maribavir is an effective inhibition of wild-type pUL97-catalyzed histone phosphorylation,IC50 3 nM. Maribavir acts effectively against HCMV and Epstein-Barr virus (EBV). |
| M10754 | Avermectin B1 | Avermectin B1 (Abamectin) is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy. |
| M10700 | RG7834 | RG7834 (RO 7020322) is a highly selective, oral HBV inhibitor that effectively inhibits HBV antigens HBsAg, HBeAg, and HBV DNA in dHepaRG cells.IC50 The values are 2.8, 2.6, and 3.2 nM, respectively. |
| M10681 | Bemnifosbuvir hemisulfate | Bemnifosbuvir hemisulfate (AT-527) is a guanosine nucleotide prodrug and a potent orally active inhibitor of HCV viral replication. Bemnifosbuvir hemisulfate effectively inhibits SARS-CoV-2 (COVID-19) infection (EC90=0.47 μM). Bemnifosbuvir hemisulfate has whole-genotype antiviral activity. |
| M10646 | GRP-60367 | GRP-60367 is a first-in-class potent and selective inhibitor of rabies virus (RABV) entry that specifically targets the RABV G protein. |
| M10594 | PF-07321332 (Nirmatrelvir) | PF-07321332 (Nirmatrelvir) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme. |
| M10574 | Indolicidin | Indolicidin is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils. |
| M10543 | Tenuazonic acid | Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate. |
| M10502 | ELQ-300 | Elq-300 is an antimalarial drug available for biological research and is also an effective oral cytochrome BC1 complex (CYT BC1) reduction (Qi) site inhibitor. |
| M10444 | Oteseconazole | Oteseconazole (VT-1161) is an antifungal compound with oral activity that is highly selective for CYP51. It can effectively bind to and inhibit CYP51 of N. albicans (Kd <39 nM), but shows no obvious effect on human CYP51 |
| M10360 | Arteannuin B | Arteannuin B co-occurs with artemisinin, Arteannuin B shows anti-SARS-CoV-2 potential with an EC50 of 10.28 μM. |
| M10359 | Dihydroartemisinic acid | Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria. |
| M10339 | Fexinidazole | Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent. |
| M10232 | Cefotaxime | Cefotaxime is an inhibitor of penicillin binding protein. |
| M10217 | Sodium diethyldithiocarbamate | Sodium diethyldithiocarbamate is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection. |
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