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YH-53

Cat. No. M10884

All AbMole products are for research use only, cannot be used for human consumption.

YH-53 Structure
Size Price Availability Quantity
5mg USD 450  USD450 In stock
10mg USD 650  USD650 In stock
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Quality Control & Documentation
Biological Activity

YH-53 IS AN EFFECTIVE ONE 3CLpro Inhibitor, 3CL against SARS-CoV-1pro and SARS-CoV-2 3CLpro target Ki The values are 6.3 nM and 34.7 nM, respectively. YH-53 strongly blocks SARS-CoV-2 replication. YH-53 is a peptide-mimetic compound with unique benzothiazolidinone.

Chemical Information
Molecular Weight 575.68
Formula C30H33N5O5S
CAS Number 1471484-62-4
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yoshihiro Kawaoka, et al. Res Sq. Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2

[2] Jennifer L McKimm-Breschkin, et al. Antiviral Res. COVID-19, Influenza and RSV: Surveillance-informed prevention and treatment - Meeting report from an isirv-WHO virtual conference

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Keywords: YH-53 supplier, Anti-infection, inhibitors, activators

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