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Myriocin

Cat. No. M11199

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Myriocin  Structure
Synonym:

Thermozymocidin; ISP-I

Size Price Availability Quantity
1mg USD 148  USD148 In stock
5mg USD 250  USD250 In stock
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Quality Control & Documentation
Biological Activity

Myriocin, a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent serine-palmitoyl-transferase Inhibitors are the key to the synthesis of sphingolipids from scratch. Myriocin strongly inhibits replication of subgenomic HCV-1b replicators and JFH-1 strains of genotype 2a infectious HCV, inhibiting HCV infection IC50 3.5 μg/mL.

Chemical Information
Molecular Weight 401.54
Formula C21H39NO6
CAS Number 35891-70-4
Form Solid
Solubility (25°C) DMSO ≥ 40mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Amanda N Davis, et al. J Anim Sci. Effects of serine palmitoyltransferase inhibition by myriocin in ad libitum-fed and nutrient-restricted ewes

[2] Paola Signorelli, et al. Cell Signal. Myriocin modulates the altered lipid metabolism and storage in cystic fibrosis

[3] Ilaria Piano, et al. Front Neurosci. Myriocin Effect on Tvrm4 Retina, an Autosomal Dominant Pattern of Retinitis Pigmentosa

[4] Rui-Xu Yang, et al. Lipids Health Dis. Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis

[5] Chiara Bianca Maria Platania, et al. Drug Deliv. Novel ophthalmic formulation of myriocin: implications in retinitis pigmentosa

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Keywords: Myriocin , Thermozymocidin; ISP-I supplier, Anti-infection, inhibitors, activators

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