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RG7834

Cat. No. M10700

All AbMole products are for research use only, cannot be used for human consumption.

RG7834 Structure
Synonym:

RO 7020322

Size Price Availability Quantity
5mg USD 90  USD90 In stock
10mg USD 150  USD150 In stock
50mg USD 530  USD530 In stock
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Quality Control & Documentation
Biological Activity

RG7834 (RO 7020322) is a highly selective, oral HBV inhibitor that effectively inhibits HBV antigens HBsAg, HBeAg, and HBV DNA in dHepaRG cells.IC50 The values are 2.8, 2.6, and 3.2 nM, respectively.

Chemical Information
Molecular Weight 401.45
Formula C22H27NO6
CAS Number 2072057-17-9
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Liren Sun, et al. Antimicrob Agents Chemother. The Dihydroquinolizinone Compound RG7834 Inhibits the Polyadenylase Function of PAPD5 and PAPD7 and Accelerates the Degradation of Matured Hepatitis B Virus Surface Protein mRNA

[2] Neha Nagpal, et al. Cell Stem Cell. Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells

[3] Xingchun Han, et al. J Med Chem. Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action

[4] Henrik Mueller, et al. J Hepatol. A novel orally available small molecule that inhibits hepatitis B virus expression

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  Catalog
Abmole Inhibitor Catalog




Keywords: RG7834, RO 7020322 supplier, Anti-infection, inhibitors, activators

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