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Anti-infection Anti-infection

Cat.No.  Name Information
M1959 Oseltamivir Oseltamivir is a potent and selective inhibitor of influenza virus neuraminidase enzyme.
M5055 Peramivir Peramivir is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
M5083 β-Cyclodextrin β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
M1707 Entecavir Monohydrate Entecavir Hydrate is a class of antiviral compounds.
M3357 Telbivudine Telbivudine is an antiviral compound used in hepatitis B research.
M1695 Cidofovir Cidofovir (Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis.
M4718 Dendrobine Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine has antiviral activity against influenza A virus, IC50 values for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2) were 3.39 μM, 2.16 μM and 5.32 μM, respectively.
M10421 Sodium citrate (dihydrate) Sodium citrate dehydrate is an anticoagulant and also used as a buffer and food preservatives.
M3222 Peramivir Trihydrate Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
M4789 Isoscopoletin Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in artemisia argyi leaves. Isoscopoletin showed significant inhibition of cell proliferation, with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and CEM/ADR5000 drug-resistant subline, respectively. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication.
M43911 Tachyplesin I Tachyplesin I is a cationic antimicrobial peptide containing 17 amino acid residues.
M40724 3-Chloro-L-alanine 3-Chloro-L-alanine is an inhibitor of kynureninase as well as an inhibitory amino acid analog that inhibits the activity of several enzymes (e.g. threonine deaminase, alanine racemase).
M40629 Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is a cytomegalovirus CMV replication inhibitor, chelator, heavy metal detoxifier (e.g., acute cadmium toxicity), and radioactivity promoter, which improves solubility by forming water-soluble chelates with polyvalent cations.
M40613 Methylenedisalicylic acid Methylenedisalicylic acid is a potent inhibitor of MarR family transcription factor A (MgrA) and Ser/Thr kinase (Stp1) that enhances SarA/MgrA phosphorylation through inhibition of Staphylococcus aureus Stp1, with an IC50 value of 9.68 ± 0.52 μM when acting on Stp1.In addition, Methylenedisalicylic acid can also be used as a lead compound in the study of methods to reduce staphylococcal toxicity.
M38807 Umifenovir Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro.
M38764 Indinavir Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CLpro inhibitor.
M31392 alpha-Terpineol alpha-Terpineol is a monoterpene alcohol with broad-spectrum antitumor activity that blocks the expression of NF-kB in tumor cell growth.
M31341 Omiganan TFA Omiganan is a novel synthetic cationic antimicrobial peptide containing 12 amino acids, as well as a synthetic analog of indolemycin, with broad-spectrum antimicrobial and antibiofilm activity. It can be used in studies related to atopic rhinitis.
M31340 Peceleganan acetate Peceleganan (antimicrobial peptide PL-5) is a chemically synthesized, alpha-helical antimicrobial peptide containing 26 amino acid residues.
M28454 NVR 3-778  NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM (capsid assembly modulator) belonging to the SBA (sulfamoylbenzamide) class, with anti-HBV activity.
M25467 Aflatoxin B1 Aflatoxin B1 (AFB1) is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation.
M25433 FR901379 FR901379 is an antifungal lipopeptide.
M25429 Rezafungin acetate Rezafungin acetate is a novel echinocandin-based antifungal agent with potent antifungal activity against Candida, Aspergillus and Pneumocystis.
M25408 Epimedokoreanin B Epimedokoreanin B is a natural flavonoid, which inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated apoptosis accompanied by autophagosome accumulation. Epimedokoreanin B has anticancer, anti-inflammatory and antibacterial activity.
M25391 Dusquetide Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection.
M21632 Prochloraz Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC50 values of 25 μM, 4 μM and 0.3 μM, respectively.
M21218 Sapienic acid sodium Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively.
M20980 Emodepside Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.
M20895 Chlorobutanol Chlorobutanol (trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
M20785 Ledipasvir acetone Ledipasvir (GS-5885) acetone is the active ingredient of Ledipasvir. Ledipasvir is a potent, oral active inhibitor of the hepatitis C virus (HCV) NS5A with EC50 of 31 pM and 4 pM against GT1a and GT1b replicon, respectively.




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