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Telbivudine

Cat. No. M3357
Telbivudine Structure
Synonym:

Epavudine; L-Thymidine; NV 02B

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
5mg USD 29.6  USD37 In stock
10mg USD 52  USD65 In stock
50mg USD 156  USD195 In stock
100mg USD 216  USD270 In stock
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Quality Control
Biological Activity

Telbivudine is an antiviral compound used in hepatitis B research.

Product Citations
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 242.23
Formula C10H14N2O5
CAS Number 3424-98-4
Purity >99%
Solubility DMSO 45 mg/mL
Water 30 mg/mL
Storage at -20°C
References

[1] No authors listed. Telbivudine

[2] David Yiu-Kuen But, et al. Safety evaluation of telbivudine

[3] Kathryn Nash. Telbivudine in the treatment of chronic hepatitis B

[4] Susan J Keam. Telbivudine

[5] Jules Dienstag, et al. Telbivudine

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Keywords: Telbivudine, Epavudine; L-Thymidine; NV 02B supplier, Anti-infection, inhibitors

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