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N-Glycolylneuraminic acid

Cat. No. M19972
N-Glycolylneuraminic acid Structure
Synonym:

NeuGc; GcNeu

Size Price Availability Quantity
5mg USD 115  USD115 In stock
10mg USD 185  USD185 In stock
25mg USD 325  USD325 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 325.27
Formula C11H19NO10
CAS Number 1113-83-3
Purity >99%
Solubility Water ≥ 60 mg/mL
Storage at -20°C
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Keywords: N-Glycolylneuraminic acid, NeuGc; GcNeu supplier, Anti-infection, inhibitors

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