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Abacavir

Cat. No. M5049

All AbMole products are for research use only, cannot be used for human consumption.

Abacavir Structure
Size Price Availability Quantity
10mg USD 40  USD40 In stock
25mg USD 60  USD60 In stock
50mg USD 80  USD80 In stock
100mg USD 100  USD100 In stock
200mg USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Abacavir is a nucleoside reverse transcriptase inhibitor marketed since 1999 for the treatment of infection with the human immunodeficiency virus type 1 (HIV). Abacavir is a Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of abacavir is as a Nucleoside Reverse Transcriptase Inhibitor. The chemical classification of abacavir is Nucleoside Analog. Abacavir is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS.

Chemical Information
Molecular Weight 286.33
Formula C14H18N6O
CAS Number 136470-78-5
Form Solid
Solubility (25°C) DMSO 90 mg/mL
Water ~1 mg/mL (Need ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Charneira C,et.al. Chem Res Toxicol. Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity.

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Keywords: Abacavir supplier, HIV Protease, inhibitors, activators

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