| Cat.No. | Name | Information |
|---|---|---|
| M55542 | Ritonavir-13c,d3 | Ritonavir-13c,d3 |
| M22445 | Fosamprenavir | Fosamprenavir |
| M21645 | Tipranavir | Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC50s of 66-410 nM. |
| M21426 | BRD-K98645985 | BRD-K98645985 is a mammalian SWI/SNF transcriptional repressor inhibitor with an EC50 of ~2.37 µM. BRD-K98645985 binds ARID1A-specific BAF complex, prevents nucleosome localization, effectively reverses HIV-1 latency, and has no T-cell toxicity. |
| M21114 | Lenacapavir | Lenacapavir(GS-6207) is a first-in-class, long-acting HIV capsid inhibitor. Lenacapavir has anti-HIV activity with an EC50 of 100 pM in MT-4 cells and a mean EC50 of 50 pM (20-160 pM) against 23 clinical isolates of HIV-1 from different subtypes in peripheral blood mononuclear cells. |
| M19349 | Hinokinin | Hinokinin (Cubebinolide) is a compound isolated from the stems of Hypoestes aristate. Hinokinin exhibits moderate activity of HIV-1 protease enzyme. |
| M13489 | Nelfinavir | Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor (Ki=2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent. |
| M11497 | Trilobatin | Trilobatin (P-phlorizin) is a natural flavonoid lipid molecule that is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and has antioxidant and anti-inflammatory effects. Trilobatin is also an SGLT1/2 inhibitor that selectively induces human hepatoblastoma cell proliferation. |
| M11422 | Sodium copper chlorophyllin B | Sodium Copper ch-ch-lin B has antiviral activity against both influenza virus and HIV with an IC50s of 50 to 100 μM. |
| M10758 | ZL0580 | ZL0580 is a structural analogue of ZL0590 that induces epigenetic suppression of HIV by selectively binding to the BRD4 domain of BD1. ZL0580 induces inhibition of HIV by inhibiting Tat transcriptional activation and transcriptional prolongation, as well as inducing inhibition of chromatin structures on an HIV promoter. |
| M10683 | IMB-301 | IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G), interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G. IMB-301 inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM). Human APOBEC3G is a restriction factor that inhibits human immunodeficiency 1 virus (HIV-1) replication. |
| M10371 | Cabotegravir | Cabotegravir, also known as S/GSK1265744 or GSK744, is potent HIV integrase inhibitor. |
| M10364 | Tenofovir hydrate | Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. |
| M10325 | Diphyllin | Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. |
| M10217 | Diethyldithiocarbamate sodium | Sodium diethyldithiocarbamate is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection. |
| M10208 | Apelin-36(rat, mouse) TFA | Apelin-36(rat, mouse) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. |
| M10207 | HIV-1 TAT Peptide TFA | TAT TFA is a cell-penetrating peptide which derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1). |
| M9491 | BMS-538203 | BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent. |
| M8972 | BMS-626529 | BMS-626529 is a potent HIV-1 attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4(+) T cells. |
| M6274 | Tenofovir Disoproxil | Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. |
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