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Lenacapavir

Cat. No. M21114

All AbMole products are for research use only, cannot be used for human consumption.

Lenacapavir  Structure
Synonym:

GS-6207

Size Price Availability Quantity
1mg USD 330  USD330 In stock
5mg USD 600  USD600 In stock
10mg USD 1200  USD1200 In stock
25mg USD 1800  USD1800 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Lenacapavir(GS-6207) is a first-in-class, long-acting HIV capsid inhibitor. Lenacapavir has anti-HIV activity with an EC50 of 100 pM in MT-4 cells and a mean EC50 of 50 pM (20-160 pM) against 23 clinical isolates of HIV-1 from different subtypes in peripheral blood mononuclear cells.

Chemical Information
Molecular Weight 968.28
Formula C39H32ClF10N7O5S2
CAS Number 2189684-44-2
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] No authors listed. Lenacapavir

[2] Julia Paik. Drugs. Lenacapavir: First Approval

[3] Maria E Cilento, et al. Viruses. Drug Interactions in Lenacapavir-Based Long-Acting Antiviral Combinations

[4] Sorana Segal-Maurer, et al. N Engl J Med. Capsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection

[5] Hadas Dvory-Sobol, et al. Curr Opin HIV AIDS. Lenacapavir: a first-in-class HIV-1 capsid inhibitor

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Keywords: Lenacapavir , GS-6207 supplier, HIV Protease, inhibitors, activators

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