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Des(benzylpyridyl) Atazanavir

Cat. No. M2605
Des(benzylpyridyl) Atazanavir Structure
Synonym:

FT-0665859

Size Price Availability
10mg USD 99  USD110 1-2 Weeks
50mg USD 288  USD320 1-2 Weeks
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Des(benzylpyridyl) Atazanavir is a HIV protease inhibitor, the N-dealkylated metabolite (M1) of Atazanavir (A790051).

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 537.65
Formula C26H43N5O7
CAS Number 1192224-24-0
Purity >98%
Solubility DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Des(benzylpyridyl) Atazanavir, FT-0665859 supplier, HIV Protease, inhibitors

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