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BMS-663068 is the phosphonooxymethyl prodrug of BMS626529, a novel small-molecule attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells with EC50 of < 10 nM.
| Molecular Weight | 583.49 |
| Formula | C25H26N7O8P |
| CAS Number | 864953-29-7 |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Michael Kozal, et al. Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection
[2] Mary C Cambou, et al. Novel Antiretroviral Agents
[3] Ester Ballana, et al. BMS-663068, a safe and effective HIV-1 attachment inhibitor
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