Free shipping on all orders over $ 500

WAY-278459-A

Cat. No. M20054
WAY-278459-A Structure
Size Price Availability
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

WAY-278459-A is a inhibitor of wild type and mutant HIV-1 reverse transcriptase

Chemical Information
Molecular Weight 220.29
Formula C11H12N2OS
CAS Number 105512-88-7
Solubility (25°C) DMSO 10mM
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Related Products
Olezarsen

Olezarsen, an N-acetylgalactosamine (GalNAc)-suffixed antisense oligonucleotide (ASO) targeting hepatic APOC3 mRNA, inhibits the production of apolipoprotein C-III (apoC-III) and can be used in studies related to familial celiac sprue syndrome (FCS).

Lumasiran

Lumasiran is a siRNA compound that reduces hepatic oxalate production by targeting ethanoic acid oxidase.

Givosiran

Givosiran is a small interfering RNA that targets hepatic aminofibrillar synthase 1 (ALAS1) messenger RNA, down-regulates ALAS1 mRNA, and prevents the accumulation of neurotoxic α-aminofibrillar acids and porphyrins, which can be used in porphyria-related studies.

Viltolarsen

Viltolarsen is a phosphorodiamidomorpholine antisense oligonucleotide that targets splicing of exon 53 of the myotonic dystrophy protein gene and can be used in the study of Duchenne muscular dystrophy (DMD).

Golodirsen

Golodirsen is a phosphodiesteric morpholino oligomer (PMO) that specifically targets exon 53 of the pre-protein mRNA of myotonic dystrophy protein culture proteins, and can be used in studies related to Duchenne muscular dystrophy (DMD).

  Catalog
Abmole Inhibitor Catalog




Keywords: WAY-278459-A supplier, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.