WAY-300700 is a HIV-1 non-nucleoside reverse transcriptase inhibitor.
|Solubility (25°C)||DMSO 10mM|
Powder -20°C 3 years ; 4°C 2 years
In solvent -80°C 6 months ; -20°C 1 month
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Related HIV Protease Products|
|Ganoderic acid GS-1
Ganoderic acid GS-1, a highly oxygenated lanostane-type triterpenoid, has anti-HIV-1 protease activities with an IC50 of 58 μM.
8-Prenylluteone is a HIV-1 protease inhibitor, with an IC50 of 4 μM.
HIV-1 protease-IN-9 is a HIV-1 protease inhibitor, with a Ki of 0.028 nM.
HIV-1 protease-IN-12 is a HIV-1 protease inhibitor with an IC50 of 0.51 nM.
HIV-1 protease-IN-11 is a HIV-1 protease inhibitor with an IC50 of 0.41 nM.
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