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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M2909 Oxybutynin Hydrochloride Oxybutynin Hydrochloride is an anticholinergic compound used to relieve urinary and bladder load.
M2901 Otilonium Bromide Otilonium bromide is an antimuscarinic.
M2836 Mepenzolate Bromide Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. Mepenzolate bromide is a GPR109A inhibitor. Mepenzolate is a post-ganglionic parasympathetic inhibitor, it decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon.
M2762 Hyoscyamine Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.
M2758 Homatropine Methylbromide Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
M2757 Homatropine Bromide Homatropine Bromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
M2754 Hexamethonium Bromide Hexamethonium Bromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.
M2753 Hemicholinium 3 Hemicholinium 3 is a compound which blocks the reuptake of choline by the high-affinity choline transporter (ChT) at the presynapse. Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a Ki value of 25 nM.
M2642 Diphemanil Methylsulfate Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).
M2636 Dicyclomine hydrochloride Dicycloamine is an anticholinergic compound, a chemical released by nerves that stimulate muscle by blocking acetylcholine receptors on smooth muscle, a type of muscle.
M2615 Decamethonium Bromide Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.
M2613 Darifenacin hydrobromide Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9.
M2517 Choline Chloride Choline chloride is a quaternary ammonium salt used as an additive for animal feed.
M2441 Benzethonium Chloride Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits α4β2 nAChRs and α7 nAChRs with IC50 of 49 nM and 122 nM, respectively.
M2397 Anisotropine Methylbromide Anisotropine Methylbromide is a quaternary ammonium compound, inhibits endothelial with IC50 of 162.5 nM and 170.3 nM, respectively.
M2368 Aclidinium Bromide Aclidinium Bromide is a novel long-acting muscarinic antagonist that binds to the human muscarinic receptors AChR M1, M2, M3, M4, and M5 with Ki values of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM, and 0.16 nM, respectively. It can be used in chronic obstructive pulmonary disease (COPD) studies.
M2366 Aceclidine hydrochloride Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure.
M2268 Rocuronium bromide Rocuronium bromide (ORG 9426 Bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.
M2257 Levetiracetam Levetiracetam (UCB L059) is an antiepileptic, it is also a selective M2 muscarinic acetylcholine receptors (mAChR) inhibitor.
M2244 Biperiden hydrochloride Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system.




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