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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M3046 Tacrine hydrochloride Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist.
M3034 Succinylcholine Chloride Dihydrate Succinylcholine Chloride Dihydrate is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.
M3025 Solifenacin succinate Solifenacin succinate is an anti-muscarinic urinary spasmolysis compound. Solifenacin Succinate (YM905) is a novel muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.
M2957 Pridinol Methanesulfonate Pridenol mesylate is used as an anticholinergic compound and an antiparkinsonian compound.
M2947 Pipenzolate Bromide Pipenzolate is an antimuscarinic, which binds to muscarinic receptors as an antagonist therefore preventing acetyl choline from binding to the receptors.
M2939 Physostigmine Salicylate Physostigmine is a parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor.
M2909 Oxybutynin Hydrochloride Oxybutynin Hydrochloride is an anticholinergic compound used to relieve urinary and bladder load.
M2901 Otilonium Bromide Otilonium bromide is an antimuscarinic.
M2836 Mepenzolate Bromide Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. Mepenzolate bromide is a GPR109A inhibitor. Mepenzolate is a post-ganglionic parasympathetic inhibitor, it decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon.
M2762 Hyoscyamine Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.
M2758 Homatropine Methylbromide Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
M2757 Homatropine Bromide Homatropine Bromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively.
M2754 Hexamethonium Bromide Hexamethonium Bromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.
M2753 Hemicholinium 3 Hemicholinium 3 is a compound which blocks the reuptake of choline by the high-affinity choline transporter (ChT) at the presynapse. Hemicholinium 3 is a competitive inhibitor of the high affinity choline transporter (HACU) with a Ki value of 25 nM.
M2642 Diphemanil Methylsulfate Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR).
M2636 Dicyclomine hydrochloride Dicycloamine is an anticholinergic compound, a chemical released by nerves that stimulate muscle by blocking acetylcholine receptors on smooth muscle, a type of muscle.
M2615 Decamethonium Bromide Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.
M2613 Darifenacin hydrobromide Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9.
M2517 Choline Chloride Choline chloride is a quaternary ammonium salt used as an additive for animal feed.
M2441 Benzethonium Chloride Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits α4β2 nAChRs and α7 nAChRs with IC50 of 49 nM and 122 nM, respectively.




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