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Hyoscyamine

Cat. No. M2762
Hyoscyamine Structure
Synonym:

Daturine

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 45  USD50 In stock
50mg USD 30.6  USD34 In stock
100mg USD 45  USD50 In stock
200mg USD 55.8  USD62 In stock
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Quality Control
Biological Activity

Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 289.37
Formula C17H23NO3
CAS Number 101-31-5
Purity >99%
Solubility DMSO 48 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Hyoscyamine, Daturine supplier, AChR/AChE, inhibitors

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