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Carbachol chloride

Cat. No. M2489
Carbachol chloride Structure
Synonym:

Carbamylcholine

Size Price Availability Quantity
10mg USD 27  USD30 In stock
50mg USD 45  USD50 In stock
100mg USD 55.8  USD62 In stock
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Quality Control
Biological Activity

Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.

Customer Product Validations & Biological Datas
Source Customer experimental result (2018).
Method Western blot
Cell Lines
Concentrations 10 uM
Incubation Time 0-120 mins
Results Western blot results showed that Carbachol has a good inhibitory effect on PKD1.
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 182.65
Formula C6H15N2O2.Cl
CAS Number 51-83-2
Purity 100.00%
Solubility Water 20 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Carbachol chloride, Carbamylcholine supplier, AChR/AChE, inhibitors

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