About 11 results found for searched term "51-83-2" (0.075 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1867 | PAC-1 | Caspase |
| Procaspase activating compound 1 | ||
| PAC-1 is a procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC50 = 0.22 μM). | ||
| M2489 | Carbachol chloride | AChR/AChE |
| Carbamylcholine | ||
| Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. | ||
| M2717 | Galeterone | Androgen Receptor |
| TOK-001 | ||
| Galeterone is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth. | ||
| M5226 | UMI-77 | Bcl-2 |
| UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family. | ||
| M5318 | Zoligratinib | EGFR/HER2 |
| CH5183284;Debio 1347 | ||
| CH5183284 is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1. | ||
| M6338 | 3-MATIDA | GluR |
| 3-MATIDA is a potent, selective mGlu 1 antagonist. | ||
| M8353 | SPA0355 | Others |
| SPA0355 inhibits cytokine and LPS-induced activation of NF-kB in cell-based assays, blocking IKK-2 phosphorylation, degradation, and p65 binding to DNA. | ||
| M11529 | Temuterkib | ERK |
| LY3214996 | ||
| Temuterkib (LY3214996) is a selective, novel erK1/2 inhibitor with an IC50 of 5 nM against ERK1 and ERK2. It can effectively inhibit intracellular P-RSK1 in cancer cell lines with BRAF and RAS mutations. Temuterkib has strong antitumor activity in cancer models with altered MAPK pathways. | ||
| M13923 | CCR2-RA-[R] | CCR |
| CCR2-RA-[R] is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM. | ||
| M39160 | Xanthopurpurin | MMP |
| Xanthopurpurin, an anthraquinone glycoside, isolated from the roots of Rubia akane, shows mainly strong inhibition of collagen-induced platelet aggregation. | ||
| M50777 | Angiotensin A | Others |
| Angiotensin A is a renin–angiotensin system (RAS) peptide that causes a vasoconstrictive effect dependent on AT1 receptors. | ||
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