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Aclidinium Bromide

Cat. No. M2368
Aclidinium Bromide Structure
Synonym:

LAS 34273; LAS-W 330

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
5mg USD 47.7  USD53 In stock
10mg USD 81  USD90 In stock
50mg USD 243  USD270 In stock
100mg USD 405  USD450 In stock
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Quality Control
Biological Activity

Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 564.55
Formula C26H30NO4S2.Br
CAS Number 320345-99-1
Purity >99%
Solubility DMSO 43 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Aclidinium Bromide, LAS 34273; LAS-W 330 supplier, AChR/AChE, inhibitors

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