Cat.No. | Name | Information |
---|---|---|
M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
M56249 | Tolterodine | Tolterodine(PNU-200583) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo. |
M56248 | N-Demethyl MK-6884 | N-Demethyl MK-6884 is a potent M4 mAChR allosteric modulator. |
M56247 | AC-42 hydrochloride | AC-42 hydrochloride is the hydrochloride salt form of AC-42. |
M56246 | Rapacuronium bromide | Rapacuronium bromide (Org 9487), a non-depolarizing neuromuscular blocker, is an allosteric modulator of muscarinic acetylcholine receptor (mAChR). |
M56245 | Zamifenacin fumarate | Zamifenacin fumarate (UK-76654 fumarate) is a potent gut-selective muscarinic M3 receptor antagonist. |
M56244 | mAChR-IN-1 hydrochloride | mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM. |
M54823 | THRX-160209 | THRX-160209 is a potent antagonist at the M(2) muscarinic acetylcholine (ACh) receptor subtype that was designed using a multivalent strategy, simultaneously targeting the orthosteric site and a nearby site known to bind allosteric ligands. |
M54437 | Catestatin | Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide. |
M54385 | α-Conotoxin MII | α-Conotoxin MII (α-CTxMII), a 16-amino acid peptide from the venom of the marine snail Conus magus, potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3β2 subunits, with an IC50 of 0.5 nM. |
M54173 | COG 133 TFA | COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. |
M53102 | G-Protein antagonist peptide | G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors. |
M53101 | α-Conotoxin M I | α-Conotoxin M I is a potent and selective inhibitor of mAChR and α1β1γδ nAChR, but has no effect on nicotine-stimulated dopamine release. |
M52775 | α-Conotoxin PnIA | α-Conotoxin PnIA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease. |
M52774 | κ-Bungarotoxin | κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC50 of 2.30 nM. |
M52773 | Rabies Virus Matrix Protein Fragment(RV-MAT) | Rabies Virus Matrix Protein Fragment (RV-MAT) is a polypeptide. |
M52772 | αO-Conotoxin GeXIVA | αO-Conotoxin GeXIVA is a potent α9α10 nAChR antagonist with an IC50 of 12 nM against rat α9α10. |
M52771 | αA-Conotoxin OIVA | αA-Conotoxin OIVA (αA-OIVA) is a selective nAChR antagonist with an IC50 of 56 nM against mammalian fetal muscle nAChR. |
M52770 | αA-Conotoxin PIVA | αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. |
M52769 | α-Conotoxin AuIA | α-Conotoxin AuIA is a potent and selective α3β4 n-nAChR inhibitor. |
M52768 | α-Conotoxin BuIA | α-Conotoxin BuIA is a paralytic peptide neurotoxin and a competitive nAChR antagonist, with IC50s of 0.258 nM (α6/α3β2), 1.54 nM (α6/α3β4), 5.72 nM (α3β2), respectively. |
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