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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M56249 Tolterodine Tolterodine(PNU-200583) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo.
M56248 N-Demethyl MK-6884  N-Demethyl MK-6884 is a potent M4 mAChR allosteric modulator.
M56247 AC-42 hydrochloride  AC-42 hydrochloride is the hydrochloride salt form of AC-42.
M56246 Rapacuronium bromide Rapacuronium bromide (Org 9487), a non-depolarizing neuromuscular blocker, is an allosteric modulator of muscarinic acetylcholine receptor (mAChR).
M56245 Zamifenacin fumarate Zamifenacin fumarate (UK-76654 fumarate) is a potent gut-selective muscarinic M3 receptor antagonist.
M56244 mAChR-IN-1 hydrochloride  mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM.
M54823 THRX-160209 THRX-160209 is a potent antagonist at the M(2) muscarinic acetylcholine (ACh) receptor subtype that was designed using a multivalent strategy, simultaneously targeting the orthosteric site and a nearby site known to bind allosteric ligands.
M54437 Catestatin Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide.
M54385 α-Conotoxin MII α-Conotoxin MII (α-CTxMII), a 16-amino acid peptide from the venom of the marine snail Conus magus, potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3β2 subunits, with an IC50 of 0.5 nM.
M54173 COG 133 TFA COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide.
M53102 G-Protein antagonist peptide G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors.
M53101 α-Conotoxin M I α-Conotoxin M I is a potent and selective inhibitor of mAChR and α1β1γδ nAChR, but has no effect on nicotine-stimulated dopamine release.
M52775 α-Conotoxin PnIA α-Conotoxin PnIA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease.
M52774 κ-Bungarotoxin κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC50 of 2.30 nM.
M52773 Rabies Virus Matrix Protein Fragment(RV-MAT) Rabies Virus Matrix Protein Fragment (RV-MAT) is a polypeptide.
M52772 αO-Conotoxin GeXIVA αO-Conotoxin GeXIVA is a potent α9α10 nAChR antagonist with an IC50 of 12 nM against rat α9α10.
M52771 αA-Conotoxin OIVA αA-Conotoxin OIVA (αA-OIVA) is a selective nAChR antagonist with an IC50 of 56 nM against mammalian fetal muscle nAChR.
M52770 αA-Conotoxin PIVA αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC50 for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively.
M52769 α-Conotoxin AuIA α-Conotoxin AuIA is a potent and selective α3β4 n-nAChR inhibitor.
M52768 α-Conotoxin BuIA α-Conotoxin BuIA is a paralytic peptide neurotoxin and a competitive nAChR antagonist, with IC50s of 0.258 nM (α6/α3β2), 1.54 nM (α6/α3β4), 5.72 nM (α3β2), respectively.




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