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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M56535 Ropanicant Ropanicant (SUVN-911 free base) is a novel, potent, selective, and orally active neuronal nicotinic acetylcholine α4β2 receptor antagonist for the research of depression.
M56534 Flupyrimin  Flupyrimin acts as an antagonist at the insect nicotinic acetylcholine receptor (nAChR).
M56533 Tebanicline Tebanicline, an analogue of epibatidine, is a neuronal nicotinic acetylcholine receptor agonist.
M56532 R-(+)-Cotinine R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets.
M56531 nAChR agonist 1  nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR).
M56530 PHA 568487 free base  PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor (α-7 nAchR) agonist.
M56529 (±)-Epibatidine (±)-Epibatidine is a nicotinic agonist.
M56528 SSR180711 hydrochloride  SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist.
M56527 PHA-543613 hydrochloride  PHA-543613 hydrochloride is an oral or active α7 nAChR agonist with brain permeability, For α3β4, α1β1γδ, α4β2 and 5-HT3 receptors selective.
M56526 RJR-2429 dihydrochloride  RJR 2429 hydrochloride is a α4β2 and α7 nAChR agonist.
M56525 PHA-543613 dihydrochloride  PHA-543613 dihydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a Ki value of 8.8 nM.
M56524 Tebanicline dihydrochloride Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with potent, orally effective analgesic activity.
M56523 (±)-Anatoxin A fumarate  (±)-Anatoxin A fumarate is a potent nicotinic receptor agonist and exhibits Ki values of 1.25 nM and 1.84 μM for binding to putative α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively.
M56522 5-Iodo-A-85380 dihydrochloride 5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR.
M56255 AC-42  AC-42 is a poent M1 muscarinic selective allosteric agonist with EC50s of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively.
M56254 ASP8302  ASP8302 is a positive allosteric modulator of muscarinic M3 Receptor.
M56253 VU6019650  VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief.
M56252 LY 2033298  LY 2033298 is a selective positive allosteric modulator of the muscarinic M4 receptor.
M56251 mAChR-IN-1  mAChR-IN-1 is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM.
M56250 Zamifenacin Zamifenacin (UK-76654) is a potent gut-selective muscarinic M3 receptor antagonist.




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