Cat.No. | Name | Information |
---|---|---|
M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
M7227 | EVP-6124 hydrochloride | EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
M8888 | Donepezil | Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
M56541 | bPiDDB | bPiDDB is a potent nAChR antagonist. |
M56540 | BNC375 | BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM. |
M56539 | ABT-107 | ABT-107 is a selective α7 neuronal nicotinic receptor agonist. |
M56538 | AZD0328 | AZD0328 is a selective α7 nAChR partial agonist. |
M56537 | SUVN-911 | SUVN-911 is a potent, selective, brain penetrated and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist, with a Ki of 1.5 nM. |
M56536 | PHA 568487 | PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor (α-7 nAchR).PHA 568487 reduces neuroinflammation and oxidative stress. |
M56535 | Ropanicant | Ropanicant (SUVN-911 free base) is a novel, potent, selective, and orally active neuronal nicotinic acetylcholine α4β2 receptor antagonist for the research of depression. |
M56534 | Flupyrimin | Flupyrimin acts as an antagonist at the insect nicotinic acetylcholine receptor (nAChR). |
M56533 | Tebanicline | Tebanicline, an analogue of epibatidine, is a neuronal nicotinic acetylcholine receptor agonist. |
M56532 | R-(+)-Cotinine | R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. |
M56531 | nAChR agonist 1 | nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). |
M56530 | PHA 568487 free base | PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor (α-7 nAchR) agonist. |
M56529 | (±)-Epibatidine | (±)-Epibatidine is a nicotinic agonist. |
M56528 | SSR180711 hydrochloride | SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. |
M56527 | PHA-543613 hydrochloride | PHA-543613 hydrochloride is an oral or active α7 nAChR agonist with brain permeability, For α3β4, α1β1γδ, α4β2 and 5-HT3 receptors selective. |
M56526 | RJR-2429 dihydrochloride | RJR 2429 hydrochloride is a α4β2 and α7 nAChR agonist. |
M56525 | PHA-543613 dihydrochloride | PHA-543613 dihydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a Ki value of 8.8 nM. |
M56524 | Tebanicline dihydrochloride | Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. |
M56523 | (±)-Anatoxin A fumarate | (±)-Anatoxin A fumarate is a potent nicotinic receptor agonist and exhibits Ki values of 1.25 nM and 1.84 μM for binding to putative α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively. |
M56522 | 5-Iodo-A-85380 dihydrochloride | 5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. |
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