Cat.No. | Name | Information |
---|---|---|
M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
M56535 | Ropanicant | Ropanicant (SUVN-911 free base) is a novel, potent, selective, and orally active neuronal nicotinic acetylcholine α4β2 receptor antagonist for the research of depression. |
M56534 | Flupyrimin | Flupyrimin acts as an antagonist at the insect nicotinic acetylcholine receptor (nAChR). |
M56533 | Tebanicline | Tebanicline, an analogue of epibatidine, is a neuronal nicotinic acetylcholine receptor agonist. |
M56532 | R-(+)-Cotinine | R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. |
M56531 | nAChR agonist 1 | nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). |
M56530 | PHA 568487 free base | PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor (α-7 nAchR) agonist. |
M56529 | (±)-Epibatidine | (±)-Epibatidine is a nicotinic agonist. |
M56528 | SSR180711 hydrochloride | SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. |
M56527 | PHA-543613 hydrochloride | PHA-543613 hydrochloride is an oral or active α7 nAChR agonist with brain permeability, For α3β4, α1β1γδ, α4β2 and 5-HT3 receptors selective. |
M56526 | RJR-2429 dihydrochloride | RJR 2429 hydrochloride is a α4β2 and α7 nAChR agonist. |
M56525 | PHA-543613 dihydrochloride | PHA-543613 dihydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a Ki value of 8.8 nM. |
M56524 | Tebanicline dihydrochloride | Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. |
M56523 | (±)-Anatoxin A fumarate | (±)-Anatoxin A fumarate is a potent nicotinic receptor agonist and exhibits Ki values of 1.25 nM and 1.84 μM for binding to putative α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively. |
M56522 | 5-Iodo-A-85380 dihydrochloride | 5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. |
M56255 | AC-42 | AC-42 is a poent M1 muscarinic selective allosteric agonist with EC50s of 805 nM and 220 nM for human wild-type and Y381A mutated M1 receptors, respectively. |
M56254 | ASP8302 | ASP8302 is a positive allosteric modulator of muscarinic M3 Receptor. |
M56253 | VU6019650 | VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. |
M56252 | LY 2033298 | LY 2033298 is a selective positive allosteric modulator of the muscarinic M4 receptor. |
M56251 | mAChR-IN-1 | mAChR-IN-1 is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM. |
M56250 | Zamifenacin | Zamifenacin (UK-76654) is a potent gut-selective muscarinic M3 receptor antagonist. |
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