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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M56541 bPiDDB  bPiDDB is a potent nAChR antagonist.
M56540 BNC375  BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM.
M56539 ABT-107  ABT-107 is a selective α7 neuronal nicotinic receptor agonist.
M56538 AZD0328  AZD0328 is a selective α7 nAChR partial agonist.
M56537 SUVN-911  SUVN-911 is a potent, selective, brain penetrated and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist, with a Ki of 1.5 nM.
M56536 PHA 568487  PHA 568487 a selective agonist of alpha-7 nicotinic acetylcholine receptor (α-7 nAchR).PHA 568487 reduces neuroinflammation and oxidative stress.
M56535 Ropanicant Ropanicant (SUVN-911 free base) is a novel, potent, selective, and orally active neuronal nicotinic acetylcholine α4β2 receptor antagonist for the research of depression.
M56534 Flupyrimin  Flupyrimin acts as an antagonist at the insect nicotinic acetylcholine receptor (nAChR).
M56533 Tebanicline Tebanicline, an analogue of epibatidine, is a neuronal nicotinic acetylcholine receptor agonist.
M56532 R-(+)-Cotinine R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets.
M56531 nAChR agonist 1  nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR).
M56530 PHA 568487 free base  PHA 568487 free base is a selective alpha 7 nicotinic acetylcholine receptor (α-7 nAchR) agonist.
M56529 (±)-Epibatidine (±)-Epibatidine is a nicotinic agonist.
M56528 SSR180711 hydrochloride  SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist.
M56527 PHA-543613 hydrochloride  PHA-543613 hydrochloride is an oral or active α7 nAChR agonist with brain permeability, For α3β4, α1β1γδ, α4β2 and 5-HT3 receptors selective.
M56526 RJR-2429 dihydrochloride  RJR 2429 hydrochloride is a α4β2 and α7 nAChR agonist.
M56525 PHA-543613 dihydrochloride  PHA-543613 dihydrochloride is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a Ki value of 8.8 nM.
M56524 Tebanicline dihydrochloride Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with potent, orally effective analgesic activity.
M56523 (±)-Anatoxin A fumarate  (±)-Anatoxin A fumarate is a potent nicotinic receptor agonist and exhibits Ki values of 1.25 nM and 1.84 μM for binding to putative α4β2-type nAChR and α7-type nAChR in rat brain membranes, respectively.
M56522 5-Iodo-A-85380 dihydrochloride 5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR.




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