Cat.No. | Name | Information |
---|---|---|
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M42653 | AChE/BChE-IN-15 | AChE/BChE-IN-15 is an AChE/BChE inhibitor, with IC50s of 20 nM and 220 nM respectively. |
M42652 | TRV-7019 | TRV-7019 is a BBB-penetrable radioligand for brain imaging that target butyrylcholinesterase. |
M42651 | AChE-IN-31 | AChE-IN-31 is a non-competitive AChE inhibitor with potential for the study of Alzheimer's disease. |
M42650 | hAChE-IN-4 | hAChE-IN-4 is a potent, blood-brain barrier-permeable hAChE inhibitor with IC50 of 0.25 μM. |
M42649 | hAChE/hBACE-1-IN-1 | hAChE/hBACE-1-IN-1 is an orally active inhibitor of hAChE with blood-brain permeability. |
M42648 | Hydrangenol 8-O-glucoside | Hydrangenol 8-O-glucoside (Hydrangenol 8-O-β-D-glucopyranoside) can be isolated from Hydrangea macrophyllu. |
M42647 | Zanapezil fumarate | Zanapezil (TAK-147) fumarate is a potent, reversible and selective acetylcholine esterase (AChE) inhibitor. |
M42646 | SD-6 | SD-6 is an orally active inhibitor of hAChE and hBChE with IC50 values of 0.907 µM and 1.579 µM, respectively. |
M42644 | hBChE-IN-2 | hBChE-IN-2 is a butyrylcholinesterase (BChE) inhibitor (IC50 of 0.62 μM) and a cannabinoid receptor 2 (CB2R) agonist. |
M42643 | Octahydroaminoacridine | Octahydroaminoacridine, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor. |
M42642 | BChE-IN-17 | BChE-IN-17 is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively. |
M42641 | AChE-IN-34 | AChE-IN-34 is a potent and selective AChE inhibitor with an IC50 value of 3.98 µM with no significant inhibition against BChE. |
M42640 | BChE-IN-19 | BChE-IN-19 is a para-substituted derivative of indone (7b) with inhibitory activity of butyryl cholinesterase (BChE) (IC50=0.04 μM). |
M42639 | Methyl ganoderate A acetonide | Methyl ganoderate A acetonide, a lanostane triterpene, is a natural product that could be isolated from the fruiting bodies of Ganoderma lucidum. |
M42638 | hAChE/hBACE-1-IN-2 | hAChE/hBACE-1-IN-2 is a potent, orally active, blood-brain barrier transboundary triple inhibitor of hAChE, hBChE, and HACE-1 with IC50s of 0.113 μM, 1.48 μM and 0.38 μM, respectively. |
M42637 | SB-1436 | SB-1436 is an Cholinesterase (ChE) inhibitor, inhibits AChE, BChE and rHuAChE with IC50s of 0.176, 0.37 and 0.08 μM, respectively. |
M42214 | Tebanicline hydrochloride | Tebanicline hydrochloride (Ebanicline hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. |
M42213 | CVN417 | CVN417 is an orally active α6 subunit-containing nAChR antagonist, modulating phasic dopaminergic neurotransmission in an impulse-dependent manner. |
M42212 | Epiboxidine hydrochloride | Epiboxidine hydrochloride is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. |
M42211 | TC-1698 | TC-1698 is a selective α7 nicotinic acetylcholine receptors agonist with EC50 value of 0.16 μM and 0.46 μM for monkey α7 nicotinic receptor and human α7 nicotinic receptor, respectively. |
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