| Cat.No. | Name | Information |
|---|---|---|
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M41867 | Oxyphenonium bromide | Oxyphenonium bromide is an antiacetylcholine compound. |
| M41866 | Nitrocaramiphen hydrochloride | Nitrocaramiphen hydrochloride is a selective M1 receptor antagonist (Ki: 5.5 nM). |
| M41865 | J-104129 | J-104129 is a selective and orally active muscarinic M3 receptor antagonist (Ki = 4.2 nM). |
| M41864 | Muscarine | Muscarine ((+)-Muscarine) is a toxin that can stimulate the parasympathetic nervous system. |
| M41863 | Milameline hydrochloride | Milameline (CI 979) hydrochloride is a muscarinic receptor agonist that improves cognition. |
| M41862 | Dipeptide diaminobutyroyl benzylamide diacetate | Dipeptide diaminobutyroyl benzylamide diacetate, a Wagerlin-1-mimicking peptide, is a mAChR antagonist. |
| M41861 | VU0364572 TFA | VU0364572 TFA is an orally active and selective allosteric agonist of the M1 muscarinic receptor with an EC50 of 0.11 μM. |
| M41860 | Arecaidine but-2-ynyl ester tosylate | Arecaidine but-2-ynyl ester tosylate (ABET) is a selective mAChR M2 agonist that dose-dependently decreases mean arterial pressure and heart rate in rats. |
| M41000 | (R)-Oxybutynin | (R)-Oxybutynin is a racemic isomer of Oxybutynin and an orally active muscarinic receptor antagonist. It has antitussive and anticholinergic activity, competitively antagonizes carbachol-induced contractions, and can be used in studies related to obstructive sleep apnea (OSA). |
| M40911 | Octahydroaminoacridine succinate | Octahydroaminoacridine succinate is a Tacrine analog and a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). It may be used in studies related to Alzheimer's disease (AD). |
| M39202 | Cyclopenin | Cyclopenin ((±)-Isocyclopenine) is a racemate. |
| M39201 | Lycodoline | Lycodoline is a alkaloid with butyrylcholinesterase (BChE) (IC50 of 667 μM) inhibition activities. |
| M39200 | Vomifoliol | Vomifoliol, a compound related to abscisie acid (ABA), has a modified 2,4-pentadiene side chain and has activity equal to that displayed by ABA. Vomifoliol exhibits antiacetylcholinesterase activity and displays moderate antileishmanial activity. |
| M39199 | Isonaringin | Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE. |
| M39198 | Huperzine C | Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease. |
| M39197 | Leptomerine | Leptomerine, an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer Disease. Leptomerine inhibits acetyl cholinesterase (AChE) with an IC50 of 2.5 μM. Anticholinesterasic activity. |
| M39196 | Isorosmanol | Isorosmanol is an abietane-type diterpene isolated from Rosmarinus officinalis L. aerial parts, with antioxidant, neuroprotective and neurotrophic effects. Isorosmanol inhibits AChE activity and melanin synthesis. |
| M39195 | Broussonin A | Broussonin A is a potent BChE inhibitor, with an IC50 of 4.16 µM. Broussonin A is a diarylpropane natural product that can be isolated from the bark of Broussonetia papyrifera after solid fermentation. |
| M39194 | (-)-Corynoxidine | (-)-Corynoxidine is an acetylcholinesterase inhibitor with an IC50 value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa. (-)-Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees. |
| M39193 | Dehydrodicentrine | Dehydrodicentrine is an aporphine alkaloid can be isolated from the root of S. epigaea and has inhibitory effect on acetylcholinesterase (AChE) with an IC50 value of 2.98 μM. |
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