Cat.No. | Name | Information |
---|---|---|
M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
M20982 | BNC210 | BNC210 (H-Ile-Trp-OH, IW-2143) is a negative allosteric modulator of alpha-7 nicotinic acetylcholine receptor (α7 nAChR). |
M20957 | Cevimeline | Cevimeline (AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. |
M20926 | Clidinium Bromide | Clidinium Bromide is an anticholinergic drug. |
M20552 | Cyclopentolate Hydrochloride | Cyclopentolate is an antagonist of muscarinic acetylcholine receptors with Ki values of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively. |
M20524 | Scopolamine N-Oxide HydrobroMide Monohydrate | Scopolamine N-Oxide is a muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors. |
M20498 | Ethyl (triphenylphosphoranylidene) acetate | Ethyl (triphenylphosphoranylidene) acetate may act as an inhibitor of cholinesterase that inhibits AChE and BChE. |
M20457 | Pralidoxime Iodide | Pralidoxime Iodide (2-PAM) is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning. |
M20455 | Acotiamide | Acotiamide is a novel acetylcholinesterase inhibitor with fundus-relaxing and gastroprokinetic properties. |
M20442 | Nanofin | Nanofin is a ganglion blocker alkaloid having nicotinic acetylcholine receptor antagonist action. It has antihypertensive effect used for mild to moderate hypertension. |
M20422 | Methylbenactyzine Bromide | Methylbenactyzine Bromide is a kind of muscarinic cholinergic receptor antagonist with antispasmodic activity. |
M20416 | Benactyzine hydrochloride | Benactyzine hydrochloride is a centrally acting muscarinic antagonist. It is used as an antidepressant in the treatment of depression and associated anxiety. |
M19338 | Sparteine | (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. |
M19196 | Lycoramine | Lycoramine, a dihydro-derivative of galanthamine, is isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor. |
M19148 | (-)-Carvone | (-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae. |
M19146 | Trimyristin | Trimyristin significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively. |
M18968 | Cyclobuxine D | Cyclobuxine D has a significant bradycardic effect in the rat heart and an inhibitory action on acetylcholine and Ba++−induced contraction of the longitudinal muscle isolated from the rabbit jejunum. |
M18262 | N-Desmethyl Galanthamine | N-Desmethyl Galanthamine |
M14550 | Sinapine | Sinapine is an alkaloid isolated from seeds of the cruciferous species. |
M14546 | Drofenine hydrochloride | Drofenine hydrochloride is a potent competitive inhibitor of BChE, and the ki values of Drofenine is calculated to be 3 uM. |
M14545 | Chlorpyrifos | Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. |
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