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Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.
| Molecular Weight | 403.9 |
| Formula | C22H26ClNO4 |
| CAS Number | 1248-42-6 |
| Form | Solid |
| Solubility (25°C) | Water 100 mg/mL (ultrasonic) DMSO 83.33 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
[1] Basuli Suchand, et al. J Org Chem. Palladium-Catalyzed Environmentally Benign Acylation
| Related AChR/AChE Products |
|---|
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Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor. |
| AT 1001
AT 1001 is a high-affinity and selective antagonist of the α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) with Ki of 2.64 nM. |
| Dihydro-β-erythroidine hydrobromide
Dihydro-β-erythroidine hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. |
| Spinosad
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. |
| TAE-1
TAE-1 is a potent inhibitor of AChE and BuChE. |
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