Free shipping on all orders over $ 500

Nanofin

Cat. No. M20442
Nanofin Structure
Synonym:

2,6-Dimethylpiperidine; Lupetidine; Naniopinum

Size Price Availability
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Nanofin is a ganglion blocker alkaloid having nicotinic acetylcholine receptor antagonist action. It has antihypertensive effect used for mild to moderate hypertension.

Chemical Information
Molecular Weight 113.20
Formula C7H15N
CAS Number 504-03-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Andreas Aigner, et al. Sci Adv. Plasmonic bound states in the continuum to tailor light-matter coupling

[2] Wenqiang Deng, et al. Opt Lett. Long short-term memory neural network for directly inverse design of nanofin metasurface

[3] Ziheng Qian, et al. Opt Express. Broadband achromatic longitudinal bifocal metalens in the visible range based on a single nanofin unit cell

[4] Zheng Bo, et al. ACS Catal. Solar-Enhanced Plasma-Catalytic Oxidation of Toluene over a Bifunctional Graphene Fin Foam Decorated with Nanofin-like MnO2

[5] Mohammadreza Khorasaninejad, et al. Nat Commun. Silicon nanofin grating as a miniature chirality-distinguishing beam-splitter

Related AChR/AChE Products
Catestatin

Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide.

α-Conotoxin MII

α-Conotoxin MII (α-CTxMII), a 16-amino acid peptide from the venom of the marine snail Conus magus, potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3β2 subunits, with an IC50 of 0.5 nM.

COG 133 TFA

COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide.

α-Bungarotoxin

α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs).

G-Protein antagonist peptide

G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors.

  Catalog
Abmole Inhibitor Catalog




Keywords: Nanofin, 2,6-Dimethylpiperidine; Lupetidine; Naniopinum supplier, AChR/AChE, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.