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BNC210

Cat. No. M20982

All AbMole products are for research use only, cannot be used for human consumption.

BNC210 Structure
Synonym:

H-Ile-Trp-OH, IW-2143

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Quality Control & Documentation
Biological Activity

BNC210 (H-Ile-Trp-OH, IW-2143) is a negative allosteric modulator of alpha-7 nicotinic acetylcholine receptor (α7 nAChR).

Chemical Information
Molecular Weight 317.38
Formula C17H23N3O3
CAS Number 13589-06-5
Solubility (25°C) DMSO 63 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Adam Perkins, et al. Transl Psychiatry. Cholinergic modulation of disorder-relevant human defensive behaviour in generalised anxiety disorder

[2] Toby Wise, et al. Biol Psychiatry. Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalized Anxiety Disorder

[3] Danny Chan. IDrugs. AIMECS 09--Seventh AFMC International Medicinal Chemistry Congress. 23-27 August 2009, Cairns, Queensland, Australia

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Keywords: BNC210, H-Ile-Trp-OH, IW-2143 supplier, AChR/AChE, inhibitors, activators

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