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Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
| Molecular Weight | 208.26 |
| Formula | C11H16N2O2 |
| CAS Number | 92-13-7 |
| Form | Viscous liquid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage | -20°C, protect from light |
[1] Theresa Schmidt, et al. Molecules. Concise Synthesis of Both Enantiomers of Pilocarpine
[2] Eyal Zur. Int J Pharm Compd. Low-dose Pilocarpine Spray to Treat Xerostomia
| Related AChR/AChE Products |
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AT 1001 is a high-affinity and selective antagonist of the α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) with Ki of 2.64 nM. |
| Dihydro-β-erythroidine hydrobromide
Dihydro-β-erythroidine hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. |
| Spinosad
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. |
| TAE-1
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| PE154
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