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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M2489 Carbachol chloride Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor.
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M5683 Glycopyrrolate Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M8888 Donepezil Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.
M2397 Anisotropine Methylbromide Anisotropine Methylbromide is a quaternary ammonium compound, inhibits endothelial with IC50 of 162.5 nM and 170.3 nM, respectively.
M2368 Aclidinium Bromide Aclidinium Bromide is a novel long-acting muscarinic antagonist that binds to the human muscarinic receptors AChR M1, M2, M3, M4, and M5 with Ki values of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM, and 0.16 nM, respectively. It can be used in chronic obstructive pulmonary disease (COPD) studies.
M2366 Aceclidine hydrochloride Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure.
M2268 Rocuronium bromide Rocuronium bromide (ORG 9426 Bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.
M2257 Levetiracetam Levetiracetam (UCB L059) is an antiepileptic, it is also a selective M2 muscarinic acetylcholine receptors (mAChR) inhibitor.
M2244 Biperiden hydrochloride Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system.
M2243 Aniracetam Aniracetam is a compound that promotes intellectual development and neuroprotection.
M2170 SVT-40776 SVT-40776 is a novel M3 muscarinic receptor antagonist.
M2037 Fesoterodine fumarate Fesoterodine fumarate (Toviaz) is a novel muscarinic receptor antagonist.
M1866 VU 0255035 VU 0255035 is a highly selective M1 muscarinic acetylcholine receptor (mAChR) antagonist (Ki = 14.87 nM).
M1364 1-Benzyl-1H-indole-2,3-dione 1-Benzyl-1H-indole-2,3-dione
M58683 Methoctramine tetrahydrochloride Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor.
M58357 Dihydro-β-erythroidine hydrobromide Dihydro-β-erythroidine hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively.
M56811 TAE-1  TAE-1 is a potent inhibitor of AChE and BuChE.
M56810 PE154  PE154 is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively).
M56809 AChE-IN-23  AChE-IN-23 is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM.
M56808 Carlina oxide  Carlina oxide is an AChE inhibitor and antioxidant that kills Culex pipiens larvae (LC50=1.39 μg/mL).
M56807 Ambenonium chloride Ambenonium (WIN 8077) chloride is an orally active and reversible inhibitor of Acetyicholinesterase (AChE) with high affinity.
M56806 Pseudocoptisine acetate Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber.
M56805 Pseudocoptisine chloride Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber.




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