| Cat.No. | Name | Information |
|---|---|---|
| M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
| M7227 | EVP-6124 hydrochloride | EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
| M8888 | Donepezil | Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
| M6941 | McN-A 343 | McN-A 343 is a selective M 1 muscarinic agonist. |
| M6350 | 5-Methylfurmethiodide | 5-Methylfurmethiodide is a potent muscarinic agonist. |
| M6341 | 4-Acetyl-1,1-dimethylpiperazinium iodide | 4-Acetyl-1,1-dimethylpiperazinium iodide is a nicotinic agonist. |
| M6335 | 3-Bromocytisine | 3-Bromocytisine is a potent agonist of α4β4, α4β2 and α7 nACh receptors. |
| M6273 | Varenicline tartrate | Varenicline Tartrate is a nicotinic AChR partial agonist, used to treat nicotine addiction. |
| M6268 | Varenicline | Varenicline (CP 526555) is a selective α4β2 nicotinic receptor partial agonist, it stimulates nicotine receptors more weakly than nicotine itself does. |
| M6127 | TD-4208 | Revefenacin (TD-4208; GSK1160724) is a novel and potent muscarinic receptor antagonist that has a high affinity and long residence time at the M3 receptor, and demonstrates in vitro kinetic selectivity for M3 over M2 muscarinic receptor subtype and no meaningful off-target activity. |
| M6040 | Tropicamide | Tropicamide (Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM. |
| M6032 | Trihexyphenidyl hydrochloride | Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity. |
| M6017 | Tiotropium Bromide hydrate | Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. |
| M6016 | Tiotropium Bromide | Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. |
| M5970 | Solifenacin HCl | Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist. |
| M5937 | Rivastigmine (tartrate) | Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease. |
| M5890 | Pralidoxime chloride | Pralidoxime is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator. |
| M5810 | Neostigmine methyl sulfate | Neostigmine methyl sulfate is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier. |
| M5776 | Methacholine chloride | Methacholine chloride is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system. |
| M5750 | Lobeline HCl | Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes. |
| M5718 | Itopride HCl | Itopride hydrochloride is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM. |
| M5673 | Gallamine Triethiodide | Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. |
| M5672 | Galanthamine HBr | Galanthamine HBr is an alkaloid derived from lithophyllum and also a reversible AChE inhibitor with an IC50 of 0.35 μM, which is 50-fold more selective than that used for butyrylcholinesterase. It can be used in studies related to Alzheimer's disease (AD). |
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