| Cat.No. | Name | Information |
|---|---|---|
| M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
| M6017 | Tiotropium Bromide hydrate | Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. |
| M6016 | Tiotropium Bromide | Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. |
| M5970 | Solifenacin HCl | Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist. |
| M5937 | Rivastigmine (tartrate) | Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease. |
| M5890 | Pralidoxime chloride | Pralidoxime is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator. |
| M5810 | Neostigmine methyl sulfate | Neostigmine methyl sulfate is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier. |
| M5776 | Methacholine chloride | Methacholine chloride is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system. |
| M5750 | Lobeline HCl | Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes. |
| M5718 | Itopride HCl | Itopride hydrochloride is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM. |
| M5673 | Gallamine Triethiodide | Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. |
| M5672 | Galanthamine HBr | Galanthamine HBr is an alkaloid derived from lithophyllum and also a reversible AChE inhibitor with an IC50 of 0.35 μM, which is 50-fold more selective than that used for butyrylcholinesterase. It can be used in studies related to Alzheimer's disease (AD). |
| M5584 | Diphenidol hydrochloride | Diphenidol hydrochloride is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the study of vomiting and vertigo. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells. |
| M5522 | Cisatracurium Besylate | Cisatracurium Besylate is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. |
| M5448 | Benzetimide | Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist. |
| M5433 | Atropine Sulfate Monohydrate | Atropine sulfate monohydrate is a competitive antagonist for the muscarinic acetylcholine receptor, used to decrease the production of saliva and secretions of the airway prior to surgery. |
| M5389 | Adiphenine HCl | Adiphenine HCl is a nicotinic receptor inhibitor with IC50 of 15 μM, used as an antispasmodic drug. |
| M5208 | Hydroxynorketamine | Hydroxynorketamine (HNK) is a metabolite of ketamine which act as a potent and selective negative allosteric modulator of the α7-nicotinic acetylcholine receptor (IC50 < 1 µM). |
| M5194 | VU0357017 hydrochloride | VU0357017 hydrochloride is a highly selective M1 agonist that appear to act at an allosteric site to activate the receptor. |
| M5046 | Imidafenacin (ONO-8025) | Imidafenacin (ONO-8025) is a urinary antispasmodic of the anticholinergic class.Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors (IC50=4.13 nM). |
| M4969 | Atracurium besylate | Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg. Atracurium besylate also is an AChR receptor antagonist. Atracurium besylate induces bronchoconstriction and neuromuscular blockade. |
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