| Cat.No. | Name | Information |
|---|---|---|
| M2489 | Carbachol chloride | Carbachol is a cholinomimetic compound that binds and activates the acetylcholine receptor. |
| M3470 | Oxybutynin | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| M3190 | PNU-282987 | PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM. |
| M5683 | Glycopyrrolate | Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
| M11348 | Garcinol | Garcinol is a kind of polyisoprene diphenylketone extracted from Garcinia japonicum. It has anticholinesterase properties for AChE and butyrylcholinesterase (BChE) with IC50 of 0.66 µM and 7.39 µM, respectively. Garcinol also inhibited histone acetyltransferases (HATs, IC50=7 μM) and P300 /CPB related factors (PCAF, IC50=5 μM). Garcinol has anti-inflammatory and anticancer activities. |
| M10928 | Rivastigmine | Rivastigmine (S-Rivastigmine) is an orally active, potent cholinesterase (ChE) inhibitor that inhibits butyrylcholinesterase (BChE) and acetylcholinesterase (AChE),IC50 0.037 μM and 4.15 μM, respectively. Rivastigmine can pass through the blood-brain barrier (BBB). Rivastigmine is an parasympathetic or cholinergic agent used to study dementia caused by mild to moderate Alzheimer's and Parkinson's disease. |
| M10906 | Xanomeline | Xanomeline increases neuronal excitability as a potent selective muscarinic 1 and type 4 (M1/M4) receptor agonist. Xanomeline can be used in the study of neurological disorders such as schizophrenia. |
| M10873 | Pirmenol hydrochloride | Pirmenol hydrochloride inhibits IK.ACh (IC50=0.1 μM) by blocking mAchR. Pirmenol hydrochloride can be used in the research of cardiovascular disease. |
| M10830 | Corynantheine | Corynantheine (Hirsuteine) is an indole alkaloid extracted from Uncaria rhynchophylla. Corynantheine (Hirsuteine) antagonizes nicotine-mediated dopamine release non-competitively by blocking ion permeation through nicotinic receptor channel complexes. |
| M10659 | Picfeltarraenin IV | Picfeltarraenin IV is an acetylcholinesterase (AChE) inhibitor, which is obtained from Picriafel-terrae Lour (P.fel-terrae). |
| M10655 | Picfeltarraegenin X | Picfeltarraenin X is an AChE inhibitor, which is a triterpenoid isolated from Picria fel-terrae Lour. |
| M10623 | Dehydronuciferine | Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn, a acetylcholinesterase (AChE) inhibitor with an IC50 of 25 μg/mL |
| M10619 | Rhodiosin | Rhodiosin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.420 μM and a Ki of 0.535 μM. Rhodiosin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL. |
| M10616 | Picfeltarraenin IA | Picfeltarraenin IA, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. |
| M10294 | Scopolamine hydrobromide trihydrate | Scopolamine hydrobromide trihydrate is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 ± 4.3 nM. |
| M10154 | Choline Glycerophosphate | Choline Glycerophosphate is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. |
| M9768 | MK-7622 | MK-7622 is a cholinesterase inhibitor, it is also a muscarinic M1 receptor positive allosteric modulator. |
| M9607 | VU0119498 | VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM). |
| M9606 | VU0238441 | VU0238441 is a potent agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM. |
| M9590 | Acotiamide dihydrochloride | Acotiamide is a potent, selective and reversible inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). |
| M9562 | Huperzine A | Huperzine A is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor extracted from traditional Chinese herb. |
| M9519 | Nelonicline | Nelonicline (ABT-126) is a nicotinic acetylcholine receptor agonist. |
| M9058 | Varenicline hydrochloride | Varenicline hydrochloride is a potent partial agonist of α4β2 nicotinic acetylcholine receptor (nAChR) and α3β4 nAChR, with EC50s of 2.3 μM and 55 μM, respectively. In addition, Varenicline hydrochloride is also a potent full agonist of α7 nAChRs. In addition, Varenicline hydrochloride is a potent full α7 nAChRs agonist with an EC50 of 18 μM. |
| M8888 | Donepezil | Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
