All AbMole products are for research use only, cannot be used for human consumption.
Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively. Epiberberine chloride has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and may protect against Alzheimer disease. Epiberberine chloride inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways. Epiberberine has the potential effect in the research of diabetic disease.
| Molecular Weight | 371.81 |
| CAS Number | 889665-86-5 |
| Solubility (25°C) | DMSO 25 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related AChR/AChE Products |
|---|
| VU 0255035
VU 0255035 is a highly selective M1 muscarinic acetylcholine receptor (mAChR) antagonist (Ki = 14.87 nM). |
| SVT-40776
SVT-40776 is a novel M3 muscarinic receptor antagonist. |
| Aniracetam
Aniracetam is a compound that promotes intellectual development and neuroprotection. |
| Aceclidine hydrochloride
Aceclidine is a parasympathomimetic miotic agent used to decreases intraocular pressure. |
| Aclidinium Bromide
Aclidinium Bromide is a novel long-acting muscarinic antagonist that binds to the human muscarinic receptors AChR M1, M2, M3, M4, and M5 with Ki values of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM, and 0.16 nM, respectively. It can be used in chronic obstructive pulmonary disease (COPD) studies. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
