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AChR/AChE Acetylcholine Receptors/Acetylcholinesterase

Cat.No.  Name Information
M3470 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
M3190 PNU-282987 PNU-282987 is a highly selective α7 nAChR agonist with Ki of 27 nM.
M7940 Mecamylamine hydrochloride Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
M7853 Ipratropium bromide monohydrate Nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.
M7585 Atropine Atropine (Tropine tropate) is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia.
M7517 Acotiamide hydrochloride Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.
M7472 VU 0365114 VU 0365114 is a positive allosteric modulator of M5 receptors.
M7227 EVP-6124 hydrochloride EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
M7141 Pirenzepine dihydrochloride Pirenzepine dihydrochloride is a selective M1 muscarinic antagonist.
M6941 McN-A 343 McN-A 343 is a selective M 1 muscarinic agonist.
M6350 5-Methylfurmethiodide 5-Methylfurmethiodide is a potent muscarinic agonist.
M6341 4-Acetyl-1,1-dimethylpiperazinium iodide 4-Acetyl-1,1-dimethylpiperazinium iodide is a nicotinic agonist.
M6335 3-Bromocytisine 3-Bromocytisine is a potent agonist of α4β4, α4β2 and α7 nACh receptors.
M6273 Varenicline tartrate Varenicline Tartrate is a nicotinic AChR partial agonist, used to treat nicotine addiction.
M6268 Varenicline Varenicline (CP 526555) is a selective α4β2 nicotinic receptor partial agonist, it stimulates nicotine receptors more weakly than nicotine itself does.
M6127 TD-4208 Revefenacin (TD-4208; GSK1160724) is a novel and potent muscarinic receptor antagonist that has a high affinity and long residence time at the M3 receptor, and demonstrates in vitro kinetic selectivity for M3 over M2 muscarinic receptor subtype and no meaningful off-target activity.
M6040 Tropicamide Tropicamide (Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.
M6032 Trihexyphenidyl hydrochloride Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity.
M6017 Tiotropium Bromide hydrate Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.
M6016 Tiotropium Bromide Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
M5970 Solifenacin HCl Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.
M5937 Rivastigmine (tartrate) Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.




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