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Propantheline bromide is an orally active mAChR antagonist that inhibits acetylcholine action at postganglionic synapses, and can be used in studies related to smooth muscle dysfunction as well as gastrointestinal spasms.
| Molecular Weight | 448.39 |
| Formula | C23H30NO3Br |
| CAS Number | 50-34-0 |
| Solubility (25°C) | Water: 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] C Baraldi, et al. IR, Raman and SERS spectra of propantheline bromide
[2] T G WHITE. Propantheline bromide in primary dysmenorrhoea
[3] No authors listed. Environ Health Perspect. Reproductive toxicology. Propantheline bromide
| Related AChR/AChE Products |
|---|
| Methoctramine tetrahydrochloride
Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor. |
| AT 1001
AT 1001 is a high-affinity and selective antagonist of the α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) with Ki of 2.64 nM. |
| Dihydro-β-erythroidine hydrobromide
Dihydro-β-erythroidine hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. |
| Spinosad
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. |
| TAE-1
TAE-1 is a potent inhibitor of AChE and BuChE. |
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