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Atropine

Cat. No. M7585
Atropine Structure
Synonym:

Tropine tropate; DL-Hyoscyamine

Size Price Availability Quantity
25mg USD 36  USD40 In stock
50mg USD 54  USD60 In stock
100mg USD 90  USD100 In stock
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Quality Control
Biological Activity

Atropine (Tropine tropate) is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 289.37
Formula C17H23NO3
CAS Number 51-55-8
Purity >98%
Solubility DMSO ≥ 30 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Atropine, Tropine tropate; DL-Hyoscyamine supplier, AChR/AChE, inhibitors

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