About 5 results found for searched term "51-55-8" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M7585 | Atropine | AChR/AChE |
Tropine tropate; DL-Hyoscyamine | ||
Atropine (Tropine tropate) is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors. Atropine inhibits ACh-induced relaxations in human pulmonary veins. Atropine can be used for research of anti-myopia and bradycardia. | ||
M16500 | Rosthornin A | Diterpenoids |
Rosthornin A | ||
M42512 | MMP13-IN-4 | MMP |
MMP13-IN-4 is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM), involved in osteoarthritis (OA). | ||
M28377 | Vevorisertib trihydrochloride | Akt |
ARQ 751 trihydrochloride | ||
Vevorisertib (ARQ 751) trihydrochloride is a selective, allosteric, pan-AKT and AKT1-E17K mutant inhibitors. Vevorisertib trihydrochloride potently inhibit phosphorylation of AKT. Vevorisertib trihydrochloride has Kd values of 1.2 nM and 8.6 nM for AKT1 and AKT1-E17K, respectively. Vevorisertib trihydrochloride has IC50 values of 0.55, 0.81, and 1.3 nM for AKT1, AKT2, and AKT3, respectively. | ||
M28378 | Vevorisertib | Akt |
ARQ 751 | ||
Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor against AKT1 (IC50=0.55 nM), AKT2 (IC50=0.81 nM), and AKT3 (IC50=1.31 nM). Vevorisertib, as a single agent or in combination with other anti-cancer agents, can be used for the research of solid tumors with PIK3CA / AKT / PTEN mutations. |
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