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Rocuronium bromide

Cat. No. M2268
Rocuronium bromide Structure
Synonym:

Zemuron, Esmeron

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mg USD 39.6  USD44 In stock
50mg USD 59.4  USD66 In stock
100mg USD 81  USD90 In stock
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Quality Control
Biological Activity

Rocuronium bromide (Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 609.68
Formula C32H53N2O4.Br
CAS Number 119302-91-9
Purity >99%
Solubility DMSO 100 mg/mL
Water 100 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Rocuronium bromide, Zemuron, Esmeron supplier, AChR/AChE, inhibitors

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