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Bethanechol chloride

Cat. No. M3309
Bethanechol chloride Structure
Synonym:

Carbamyl-β-methylcholine chloride

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
100mg USD 35.1  USD39 In stock
200mg USD 47.7  USD53 In stock
1g USD 56.7  USD63 In stock
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Quality Control
Biological Activity

Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors. It is a parasympathomimetic choline ester. It is not hydrolyzed by cholinesterase and will therefore have a long duration of action. It does not involve the action of the muscarinic M3 receptor subtype in-vitro.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 196.68
Formula C7H17N2O2.Cl
CAS Number 590-63-6
Purity >97%
Solubility DMSO 20 mg/mL
Water 30 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Bethanechol chloride, Carbamyl-β-methylcholine chloride supplier, AChR/AChE, inhibitors

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