About 30 results found for searched term "HU6" (0.024 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M40805 | Recombinant Human TPO (HEK293, N,C-6His) | Cytokines and Growth Factors |
| Thrombopoietin; THPO | ||
| Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. | ||
| M5726 | Recombinant Human CD48/SLAMF2 (HEK293,C-Fc-6His) | Cytokines and Growth Factors |
| CD48 antigen; B-lymphocyte activation marker BLAST-1 | ||
| Recombinant human CD48/SLAMF2 protein plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma. | ||
| M11359 | Recombinant Human IL-6R (CHO) | Cytokines and Growth Factors |
| IL-6RA; IL-6R1; CD126; IL-6RA | ||
| Interleukin-6 Receptor Alpha belongs to the type I cytokine receptor family. It binds specifically to IL-6 and depends on gp130 to transmit signals. Measured in a cell proliferation assay using M1 cells in the presence of 10.0 ng/ mL human IL-6, the ED50 is < 0.2 μg/mL. | ||
| M10548 | TSPC | GSK-3 |
| HUN86320 | ||
| TSPC (HUN86320) is a Glycogen Synthase Kinase-3β Inhibitor (GSK-3β Inhibitor). | ||
| M9364 | Recombinant human IL-6 (CHO-expressed) | Cytokines and Growth Factors |
| Interleukin-6; rhIL-6 | ||
| Recombinant Human IL-6 is an interleukin that in humans is encoded by the IL-6 gene and acts as both a pro-inflammatory and anti-inflammatory cytokine. | ||
| M9413 | Recombinant Human VEGF165 Protein (HEK293, C-His) | Cytokines and Growth Factors |
| Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. | ||
| M9983 | Recombinant Human IL-36RA Protein (E. coli) | Cytokines and Growth Factors |
| Interleukin-36RA; IL-1F5; IL-1-Related Protein 3 | ||
| Recombinant Human IL-36RA Protein (originally named IL-1F5) can antagonize IL-36α, β or γ-induced NF-RrpB signaling by binding to IL-1Rrp2 receptor, thereby preventing the initiation of functional signals. | ||
| M10512 | Recombinant Human IL-6 (E. coli) | Cytokines and Growth Factors |
| rHuIL-6 | ||
| Recombinant Human IL-6 is an interleukin that in humans is encoded by the IL-6 gene and acts as both a pro-inflammatory and anti-inflammatory cytokine. | ||
| M15052 | Recombinant Human 4-1BB Ligand/TNFSF (E.coli,C-6His) | Cytokines and Growth Factors |
| Tumor necrosis factor ligand superfamily member 9; | ||
| The recombinant human 4-1BB ligand was produced by the escherichia coli expression system, and the target gene encoding ARG71-GLU254 was expressed at the C-terminal as 6His marker. Accession # : P41273. | ||
| M11319 | GLP-1(7-36), amide TFA | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA | ||
| TFA is a major intestinal hormone that stimulates insulin secretion by pancreatic beta cells in response to glucose. | ||
| M11383 | Anti-human CD16 mAb | Cytokines and Growth Factors |
| Bioactivity: CD16 is FcγR ⅲ, a glycoprotein with a molecular weight of 50-70kD, a member of Ig superfamily, known to be involved in antigen-dependent cytotoxicity (ADCC). The most significant feature of CD16 is that the cleavage triggered by membrane receptors is performed by NK cells. | ||
| M11490 | Recombinant Human VEGF165 (P. pastoris) | Cytokines and Growth Factors |
| VEGF-165; Vascular Endothelial Growth Factor 165; VPF | ||
| Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. | ||
| M13400 | Recombinant Human UBA5 (E.coli, N-6His) | Cytokines and Growth Factors |
| Ubiquitin-like modifier-activating enzyme 5 | ||
| UBA5 is a member of the ubiquitin activated E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are identified as covalently binding to a variety of cellular substrates through a three-step enzymatic pathway. Ubiquitin activase (E1) plays a crucial role in the first step of activating ubiquitin or ubiquitin-like proteins in the ubiquitination pathway. | ||
| M13968 | GLP-1(7-36), amide acetate | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate | ||
| GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. | ||
| M15015 | Recombinant Human Carbonic Anhydrase 1/CA1 (E.coli,C-6His) | Cytokines and Growth Factors |
| Carbonate Dehydratase I; Carbonic Anhydrase B | ||
| The recombinant human Carbonic Anhydrase 1/CA1 protein was produced by our escherichia coli expression system, and the target gene encoding ALA2-PHE261 was expressed at the C-terminal as 6His marker. Accession # : P00915. | ||
| M15014 | Recombinant Human Carboxypeptidase M (HEK293,C-6His) | Cytokines and Growth Factors |
| Carboxypeptidase M;CPM | ||
| Carboxypeptidase M (CPM) plays important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. It is widely distributed in a variety of tissues and cells. | ||
| M15012 | Recombinant Human TIMP-2 (HEK293,C-6His) | Cytokines and Growth Factors |
| Metalloproteinase Inhibitor 2; CSC-21K | ||
| TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa. It produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-2 also has erythroid‑potentiating and cell growth promoting activities. | ||
| M15018 | Recombinant Human ACE-2 (HEK293,C-6His) | Cytokines and Growth Factors |
| Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase | ||
| Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. | ||
| M15008 | Recombinant Human Carboxypeptidase E/CPE (HEK293,C-6His) | Cytokines and Growth Factors |
| Carboxypeptidase H; Enkephalin convertase | ||
| CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. | ||
| M15066 | Recombinant Human FGF-basic (146 aa, E.coli) | Cytokines and Growth Factors |
| Fibroblast growth factor 2; FGF-2; bFGF | ||
| FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. FGF-basic acts on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. | ||
| M15072 | Recombinant Human FGF-19 (E.coli, N-6His) | Cytokines and Growth Factors |
| Fibroblast growth factor 19; FGF-19; FGF19 | ||
| Recombinant human fibroblast growth factor 19 was produced by the escherichia coli expression system, and the target gene encoding Phe27-Lys216 was expressed at the N-terminal as 6His marker. Accession # : O95750. | ||
| M15073 | Recombinant Human HGF (HEK293, C-6His) | Cytokines and Growth Factors |
| Hepatocyte growth factor; HPTA; Scatter factor | ||
| HGF is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. | ||
| M15080 | Recombinant Human OSM (E.coli, N-6His) | Cytokines and Growth Factors |
| Oncostatin-M; OSM | ||
| Recombinant human Oncostatin M is produced by escherichia coli expression system, and the target gene encoding AlA26-ARG221 was expressed at the N-terminal with 6His marker. Measured by the dose-dependent stimulation of TF-1 cells. The ED50 for this effect is 0.2-1 ng/ml. | ||
| M15098 | Recombinant Human PCSK9 (HEK293,C-6His) | Cytokines and Growth Factors |
| Proprotein Convertase Subtilisin/Kexin Type 9 | ||
| Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. Accession #: Q8NBP7. | ||
| M19977 | Recombinant Human PRCP (HEK293, C-6His) | Cytokines and Growth Factors |
| Lysosomal Pro-X Carboxypeptidase; Angiotensinase C | ||
| Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. Accession: P42785. | ||
| M19986 | Recombinant Human CXCL6 (HEK293, C-6His) | Cytokines and Growth Factors |
| C-X-C Motif Chemokine 6; Chemokine Alpha 3 | ||
| Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. Accession: P80162. | ||
| M19993 | Recombinant Human B4GALT1 (HEK293, C-6His) | Cytokines and Growth Factors |
| 1,4- galactosyltransferase, polypeptide 1; B4GalT1 | ||
| Beta1,4-Galactosyltransferase-I (B4GALT1) is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. Accession: P15291. | ||
| M20739 | TRi-1 | Others |
| HUN20688, TXNRD1 inhibitor 1 | ||
| TRi-1 (HUN20688, TXNRD1 inhibitor 1) is a potent, specific and irreversible cytosolic thioredoxin reductase 1 (TXNRD1) inhibitor with IC50 of 12 nM. TRi-1 exhibits anti-cancer activity while having little mitochondrial toxicity. | ||
| M21202 | Recombinant Human Lipocalin-2/NGAL/LCN2 (E. coli, C-6His) | Cytokines and Growth Factors |
| Neutrophil gelatinase-associated lipocalin; NGAL | ||
| Human neutrophil gelatinase-associated lipid transport protein (Lipocalin-2/NGAL/LCN2) is produced by the E. coli expression system and the target gene encoding Gln21-Gly198 has a 6His tag at the C-terminus.Protein number: P80188 | ||
| M21203 | Recombinant Human/Mouse/Rat Irisin (HEK293, C-6His) | Cytokines and Growth Factors |
| Fibronectin type III domain-containing protein 5 | ||
| Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts. | ||
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