All AbMole products are for research use only, cannot be used for human consumption.
CPE is active in the form of cleaving c-terminal amino acid residues of peptides, and therefore participates in biosynthesis of peptide hormones and neurotransmitters such as insulin and enkephalin. Membrane-associated CPE acts as a sorting receptor, targeting the regulation of secretory proteins, mainly the pituitary gland across the Golgi network and secretory granules in the prehormonal and neuropeptides into secretory pathways. Defects in the protein are associated with type 2 diabetes and can lead to impaired glucose clearance and insulin resistance.
Recombinant Human Carboxypeptidase E expressed the target gene encoding Arg42-Ser453 with a 6His tag at the C-terminus.
Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 0.05% Tween80, 250mM Glycine, 2mM EDTA, 50mM L-Arg, pH6.5.
| Form | Solution |
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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